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Autor:
Satoru Takahashi, Margarete M. S. Heck, Jeffrey K Usui, Hisashi Oishi, Yunshin Jung, Ruyi Zhou, Toshiki Kato, Masafumi Muratani
Publikováno v:
Endocrinology. 159(2)
Adenoviral gene transfer of key β cell developmental regulators including Pdx1, Neurod1, and Mafa (PDA) has been reported to generate insulin-producing cells in the liver. However, PDA insulin secretion is transient and glucose unresponsive. Here, w