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pro vyhledávání: ''
Autor:
Shuofeng Yuan, Hua-Rui Gong, Jian-Dong Huang, Xuansheng Lin, Ying Dou, Y.F. Hu, Kelvin K. W. To, Jasper Fuk-Woo Chan, Vincent Kwok-Man Poon, Smaranda Ruxandra Badea, Jingchu Hu, Zhiwei Chen, Hin Chu, Kaiming Tang, Chris Chun-Yiu Chan, Jian-Piao Cai, Wen-Jun Li, Li Liu, Xiao-lei Wang, Kwok-Yung Yuen, Baozhong Zhang, Xuechen Li, Ivan Hung, Kenn Ka-Heng Chik, Chris Chung-Sing Chan
Publikováno v:
Emerging Microbes & Infections
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The Coronavirus Disease 2019 (COVID-19) pandemic is unlikely to abate until sufficient herd immunity is built up by either natural infection or vaccination. We previously identified ten linear immunodominant sites on the SARS-CoV-2 spike protein of w
Autor:
Zhaoming Chen, Yijun Deng, Linbing Qu, Xiaodi Fan, Song Li, Xuefeng Niu, Xiaoneng Mo, Jian Han, Yunfei Chen, Feng Li, Xinglong Liu, Ling Chen, Kun Luo, Liqiang Feng, Qihong Yan, Ruitian Hou, Qian Wang, Xiaohan Huang, Ping He, Yudi Zhang, Huan Liang, Xiaoli Xiong, Pingchao Li, Haisu Yi
Publikováno v:
Emerging Microbes & Infections
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Monoclonal antibodies (mAbs) encoded by IGHV3-53 (VH3-53) targeting the spike receptor-binding domain (RBD) have been isolated from different COVID-19 patients. However, the existence and prevalence of shared VH3-53-encoded antibodies in the antibody
Autor:
Lishuang Shen, Jaclyn A. Biegel, Timothy J. Triche, Xiaowu Gai, Jennifer Dien Bard, Alexander R. Judkins
Publikováno v:
Emerging Microbes & Infections
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The SARS-CoV-2 B.1.1.7 lineage is highly infectious and as of April 2021 accounted for 92% of COVID-19 cases in Europe and 59% of COVID-19 cases in the U.S. It is defined by the N501Y mutation in the receptor binding domain (RBD) of the Spike (S) pro
Autor:
Ya na Zhou, Yong Yang, Xi Wang, Hui Wang, Rong Hui Du, Wei Zhang, Bei Li, Zhengli Shi, Xu Rui Shen, Xian-En Zhang, Qian Li, Yan Zhu, Dong Men, Peng Zhou, Hao Rui Si, Xiao lin Tong
Publikováno v:
Emerging Microbes & Infections
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Without an effective vaccine against SARS-CoV-2, the build-up of herd immunity through natural infection has been suggested as a means to control COVID-19. Although population immunity is typically estimated by the serological investigation of recove
Autor:
Lin-Lei Chen, Kwok-Yung Yuen, Shannon Wing-Ngor Au, Kin-Hang Kok, Kelvin K. W. To, Joy-Yan Lam, Xiaohui Wang
Publikováno v:
Emerging Microbes & Infections
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Given the on-going SARS-CoV-2 pandemic, identification of immunogenic targets against the viral protein will provide crucial advances towards the development of sensitive diagnostic tools and vaccination strategies. Our previous study has found that
Publikováno v:
Emerging Microbes & Infections
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Serology detection is recognized for its sensitivity in convalescent patients with COVID-19, in comparison with nucleic acid amplification tests (NAATs). This article aimed to evaluate the diagnostic accuracy of serologic methods for COVID-19 based o
Autor:
Xiaohui Wang, Kelvin K. W. To, Wan Man Wong, Jian Piao Cai, Chun Kit Yuen, Long Fung Mak, Jasper Fuk-Woo Chan, Kwok-Yung Yuen, Joy Lam, Kin-Hang Kok, Hin Chu, Dong-Yan Jin
Publikováno v:
Emerging Microbes & Infections
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The Coronavirus disease 2019 (COVID-19), which is caused by the novel SARS-CoV-2 virus, is now causing a tremendous global health concern. Since its first appearance in December 2019, the outbreak has already caused over 5.8 million infections worldw
Autor:
van Tol, Sophie, Mögling, Ramona, Li, Wentao, Godeke, Gert-Jan, Swart, Arno, Bergmans, Barbara, Brandenburg, Afke, Kremer, Kristin, Murk, Jean-Luc, van Beek, Josine, Wintermans, Bas, Reimerink, Johan, Bosch, Berend-Jan, Reusken, Chantal, Virologie, dI&I I&I-1
Publikováno v:
Emerging Microbes and Infections, 9(1), 1965. Nature Publishing Group
Emerging Microbes & Infections
article-version (VoR) Version of Record
Emerging Microbes & Infections
article-version (VoR) Version of Record
Serology is a crucial part of the public health response to the ongoing SARS-CoV-2 pandemic. Here, we describe the development, validation and clinical evaluation of a protein micro-array as a quantitative multiplex immunoassay that can identify S an
Autor:
Qiyu Sun, Huan Hao, Haiyang Qin, Qianqian Li, Youchun Wang, Jianhui Nie, Xiaoyu Li, Qiong Lu, Junkai Liu, Huan Liu, Lingling Nie, Chenyan Zhao, Jiajing Wu, Meng Wang, Changfa Fan, Li Zhang, Miao Xu, Weijin Huang
Publikováno v:
Emerging Microbes & Infections
Emerging Microbes & Infections, 9(1):680-686
Emerging Microbes & Infections, 9(1):680-686
Pseudoviruses are useful virological tools because of their safety and versatility, especially for emerging and re-emerging viruses. Due to its high pathogenicity and infectivity and the lack of effective vaccines and therapeutics, live SARS-CoV-2 ha
Autor:
Hanning Hu, Xianqun Xu, Na Yang, Fang Zheng, Shengjun Liao, Siwei Li, Guoqiang Chen, Yang Xiang, Jianbin Sun, Gang Yang, Yueting Tang, Yirong Li, Xinrui Wang, Junli Fan, Wen Xie, Xueping Qiu
Publikováno v:
Emerging Microbes & Infections
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Dynamic changes of RNA and antibodies in SARS-CoV-2 infected patients remain largely unknown, and influence factors for antibody production have not been fully clarified. In this study, consecutive throat swabs specimens (n = 1875) from 187 patients