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pro vyhledávání: '"Jonathan Hall"'
Publikováno v:
eLife, Vol 7 (2018)
G-quadruplexes are naturally-occurring structures found in RNAs and DNAs. Regular RNA G-quadruplexes are highly stable due to stacked planar arrangements connected by short loops. However, reports of irregular quadruplex structures are increasing and
Externí odkaz:
https://doaj.org/article/dba9078502184ce59f8266ecb8e9fe0b
Autor:
Natasa Savic, Femke CAS Ringnalda, Helen Lindsay, Christian Berk, Katja Bargsten, Yizhou Li, Dario Neri, Mark D Robinson, Constance Ciaudo, Jonathan Hall, Martin Jinek, Gerald Schwank
Publikováno v:
eLife, Vol 7 (2018)
The CRISPR-Cas9 targeted nuclease technology allows the insertion of genetic modifications with single base-pair precision. The preference of mammalian cells to repair Cas9-induced DNA double-strand breaks via error-prone end-joining pathways rather
Externí odkaz:
https://doaj.org/article/d383e78bf9ad4d79a251b869c68ad33c