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Peripheral Neuropathy and Hindlimb Paralysis in a Mouse Model of Adipocyte-Specific Knockout of Lkb1
Autor:
Wen Jin, Xine Shi, Jessica C. Page, Shihuan Kuang, Naagarajan Narayanan, Yan Xiong, Tizhong Shan, Zhihao Jia, Feng Yue, Riyi Shi, Meng Deng, Gongshe Yang, Chao Wang, Keping Hu
Publikováno v:
EBioMedicine
EBioMedicine, Vol 24, Iss C, Pp 127-136 (2017)
EBioMedicine, Vol 24, Iss C, Pp 127-136 (2017)
Brown adipose tissues (BAT) burn lipids to generate heat through uncoupled respiration, thus representing a powerful target to counteract lipid accumulation and obesity. The tumor suppressor liver kinase b1 (Lkb1) is a key regulator of cellular energ