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Publikováno v:
Drug Research. 71:157-165
The aim of this study is to investigate whether sitagliptin can be used as an initial drug for T2DM and to evaluate its effects on metabolic parameters in relation to its glycemic efficacies. The subjects received 25−50 mg/day sitagliptin monothera
Autor:
Daisuke Maruoka, Yuichi Koike, Takahiro Nishimura, Hideaki Nagai, Koichiro Atsuda, Masahiro Kobayashi, Haruichi Kohno
Publikováno v:
Drug Research. 70:199-205
In Japan, tuberculosis has been recognized as one of the major infections requiring urgent measures because of its high morbidity rate even now especially in elderly people suffering from tuberculosis during the past epidemic and its reactivation. He
Publikováno v:
Drug Research. 70:170-173
In the last decade, a new direction of phototherapy – the non-selective chromotherapy (NSC) with Bioptron – has become widespread in clinical physiotherapy. The aim of the study was the scientific justification of the comprehensive treatment of p
Publikováno v:
Drug Research. 68:415-420
Aim This study was carried out to record the sensitivity/resistance pattern of Escherichia coli and Klebsiella pneumoniae towards antimicrobial drugs prescribed to urinary tract infection (UTI) patients. Materials and Methods A total of 68 bacteriolo
Autor:
Yunes Panahi, Ebrahim Sahebi, Soha Namazi, Nahid Khalili, Amirhossein Sahebkar, Muhammed Majeed, Luis E. Simental-Mendía
Publikováno v:
Drug Research. 68:403-409
Introduction Curcuminoids have been shown to reduce glycemia and related complications in diabetes. In the present study, we evaluated the impact of curcuminoids plus piperine administration on glycemic, hepatic and inflammatory biomarkers in type 2
Autor:
Yuko Kase, Masami Horiguchi, Fumiko Yoshida, Saori Kurihara, Masamitu Noda, Kentaro Sugiyama, Toshimi Iiduka, Toshihiko Hirano, Shun Kameyama
Publikováno v:
Drug Research. 67:705-709
Backgrounds Folic acid dose at ≦5 mg/week has been recommended for rheumatoid arthritis (RA) patients to decrease risk of methotrexate adverse effects. However, higher doses of folic acid is used in some cases. We examined the influence of high-dos
Autor:
Andrew Leary, Thierry Clavel, Jean-Marc Edmond, Claudie Sanchez, Zahida Issiakhem, Laurence Barthe, Bruno Paillard
Publikováno v:
Drug Research. 67:647-652
Numerous iron-containing preparations are available on the market; these vary in dosage, salt, chemical state of iron (ferric or ferrous) and in the iron delivery process (immediate or prolonged-release). Tardyferon® is a prolonged-release tablet co
Autor:
Yoichiro Ogama, Nahoko Kasahara-Ito, Yuji Kumagai, Hiroyuki Fukase, Yasuki Takano, Tomohisa Saito, Kimio Terao, Yasuhiro Ohba, Noboru Nakamichi, Tomoko Ichihara, Sachiya Ikeda, Sumire Shimada
Publikováno v:
Drug Research. 67:349-357
Tofogliflozin is a selective oral inhibitor of sodium-glucose co-transporter 2 for treatment of type 2 diabetes mellitus. The pharmacokinetics, pharmacodynamics, and safety of tofogliflozin were investigated in healthy male subjects. Three studies we
Autor:
Parisa Kianpour, Amirhossein Sahebkar, Luis E. Simental-Mendía, Ramezan Jafari, Yunes Panahi, Reza Mohtashami
Publikováno v:
Drug Research. 67:244-251
Non-alcoholic fatty liver disease (NAFLD) is a common liver disease characterized by excess lipid deposition in the hepatic tissue and subsequent oxidative and inflammatory damage. Curcumin is a dietary polyphenol with lipid-modifying, antioxidant an
Autor:
Seyed-Hasan Hosseini, Habib Sadr, Mehdi Ahadi-Barzoki, Mina Islambulchilar, Mir-Jamal Hosseini, Mehdi Oraie, Hashem Yaghoubi
Publikováno v:
Drug Research. 67:183-188
Chemical substances have an important threat due to extensive use in medicine, agriculture, industry and environment. In this retrospective study, etiological and demographic characteristics of acute poisoning cases admitted to a hospital in Iran wer