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pro vyhledávání: '"Drew, R."'
Autor:
Ji-Yeon Kang, Grover P. Miller, Sun Ha Park, Chul-Ho Yun, Gunnar Boysen, Jessica H. Hartman, Drew R. Jones, So-Young Kim
Publikováno v:
Drug Metabolism Letters. 6:157-164
Coumadin (R/S-warfarin) is a highly efficacious and widely used anticoagulant; however, its highly variable metabolism remains an important contributor to uncertainties in therapeutic responses. Pharmacogenetic studies report conflicting findings on
Publikováno v:
Drug Metabolism Letters. 4:213-219
Effective coumadin (R/S-warfarin) therapy is complicated by inter-individual variability in metabolism. Recent studies have demonstrated that CYP3A isoforms likely contribute to patient responses and clinical outcomes. Despite a significant focus on