Zobrazeno 1 - 4
of 4
pro vyhledávání: '"John W.M. Martens"'
Publikováno v:
Drug Discovery Today, 24(5), 1202-1208. Elsevier Ltd.
Somatic variation in mitochondrial DNA (mtDNA) has been described in primary breast tumors, including single-nucleotide variants and variation in the number of mtDNA molecules per cell (mtDNA content). However, there is currently a gap in the knowled
Publikováno v:
Drug Discovery Today, 24(9-12), 1715-1719. Elsevier Ltd.
Circulating tumor cells (CTCs) and cell-free DNA (cfDNA) together with newer emerging liquid biopsies have a unique potential to deal with key issues in oncology. For example, they can be used to assess prognosis, direct treatment with certain kinds
Publikováno v:
Drug Discovery Today, 21(7), 1181-1188. Elsevier Ltd.
Estrogen receptor (ER)-positive breast cancer represents the majority (∼70%) of all breast malignancies. In this subgroup of breast cancers, endocrine therapies are effective both in the adjuvant and recurrent settings, although resistance remains
Publikováno v:
Drug Discovery Today. 13:481-487
The use of gene-expression microarray analysis to assess the expression levels of all the genes in the genome has tremendous potential. Important information has been obtained about many disease processes, particularly in classifying tumors in differ