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Autor:
Ademola C. Famurewa, FE Ejezie, Ekenechukwu K Maduagwuna, Abiola M Folawiyo, EE Iyare, Chioma S. Ugwu-Ejezie
Publikováno v:
Drug and Chemical Toxicology. 44:418-426
Cadmium (Cd) is a ubiquitous non-essential environmental and industrial toxicant that affects various organs in humans and experimental animals. Robust evidence confirms the contribution of oxidative stress to the pathogenesis of Cd-induced hepatic d
Autor:
Daryoush Hamidi Alamdari, B Fatemeh Nobakht, Mohammad Reza Keramati, Amirhossein Sahebkar, Mahdi Balali-Mood
Publikováno v:
Drug and Chemical Toxicology. 42:536-540
The present study aimed to evaluate serum prooxidant -antioxidant balance (PAB) in an Iranian population exposed to sulfur mustard (SM) more than 20 years ago. In this study, 42 SM-exposed subjects and 30 unexposed subjects (as controls) were recruit
Autor:
Uzma Saleem, Alia Erum, Muhammad Umar Nasir, Ume Ruqia Tulain, Farina Kanwal, Shazia Saghir, Muhammad Nasir Hayat Malik, Sajid Bashir
Publikováno v:
Drug and Chemical Toxicology. 38:300-305
The arabinoxylan from Ispaghula (Plantago ovata) husk has been proven scientifically as potential excipient. However, toxicity study of the arabinoxylan is still lacking. The present study was done to investigate the acute toxicity of arabinoxylan in
Publikováno v:
Drug and chemical toxicology. 41(2)
Stevia extracts are obtained from Stevia rebaudiana commonly used as natural sweeteners. It is ∼250-300 times sweeter than sucrose. Common use of stevia prompted us to investigate its genotoxicity in human peripheral blood lymphocytes. Stevia (acti
Autor:
Danswrang Goyary, Santa Mandal, Pronobesh Chattopadhyay, Srijita chakraborti, Nilutpal Sharma Bora, P. Srinivas Raju, Aparoop Das, R.S. Policegoudra, Pompy Patowary, Manash Pratim Pathak, Johirul Islam
Publikováno v:
Drug and chemical toxicology. 41(2)
Gramine is a natural indole alkaloid that has been isolated from different raw plants occurring mainly in Avena sativa, etc. The study was aimed to investigate the possible in vitro antioxidant, in vitro mutagenic, in vitro antimutagenic, and in vivo
Publikováno v:
Drug and Chemical Toxicology. 35:347-351
In vitro effects of different concentrations of Thiram were tested on human lymphocytes to determine, by means of the chromosome aberrations (CAs) assay, whether this fungicide could induce clastogenic damage. Evidences of the effect of Thiram on hum
Autor:
Joseph I. Okogun, Musbau Adewumi Akanji, Nasir A. Salawu, Adenike Temidayo Oladiji, Musa Toyin Yakubu, Taofeek O. Ajiboye
Publikováno v:
Drug and Chemical Toxicology. 34:109-115
The antioxidant and drug metabolizing potentials of Hibiscus anthocyanin extract in CCl(4)- induced oxidative damage of rat liver was investigated. Hibiscus anthocyanin extract effectively scavenge α-diphenyl-β-picrylhydrazyl (DPPH) radical, supero
Publikováno v:
Drug and Chemical Toxicology. 31:447-457
Low-calorie sweeteners are chemicals that offer the sweetness of sugar without the calories. Consumers are increasingly concerned about the quality and safety of many products present in the diet, in particular, the use of low-calorie sweeteners, fla
Autor:
J Otaki, K Yokokawa, T Okazaki, Kenji Taguchi, H Okawa, C Sugawara, N Sugawara, N Ikeda, H Miyake
Publikováno v:
Drug and Chemical Toxicology. 10:195-207
The effects of ingested Al on the essential metals were investigated using mice. Animals were divided into 4 groups: 1) Control, 2) Al, 3) EtOH and 4) Al+EtOH groups. Powdered commercial food, containing 1.26% P, 1.36% Ca, 70ppm Zn, 15ppm Cu, 200ppm