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Autor:
Elie El Rassy, Afroditi Karathanasi, Peeter Karihtala, Nicholas Pavlidis, Stergios Boussios, Michele Moschetta, Agne Sadauskaite
Publikováno v:
Diagnostics, Vol 9, Iss 3, p 87 (2019)
Diagnostics
Diagnostics
Poly (ADP-ribose) polymerase (PARP) inhibitors are the first clinically approved drugs designed to exploit synthetic lethality, and were first introduced as a cancer-targeting strategy in 2005. They have led to a major change in the treatment of adva