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Publikováno v:
Diagnostic Molecular Pathology. 21:143-149
BACKGROUND Cancerous inhibitor of protein phosphatase 2A (CIP2A) is highly expressed in hepatocellular carcinoma (HCC) and promotes cell proliferation, cell invasion, and aggressive tumor behavior. However, there have been few studies on the usefulne
Publikováno v:
Diagnostic Molecular Pathology. 18:30-33
HER2 gene amplification by fluorescence in situ hybridization and protein expression by immunohistochemistry (IHC) have been used for prognosis and guiding treatment of invasive ductal carcinoma of the breast with trastuzumab. Accurate evaluation of
Publikováno v:
Diagnostic Molecular Pathology. 12:96-102
We studied the MSI (microsatellite instability) status and p53 expression in a series of 71 gallbladder cancers (GCs) of different histologic type. All neoplasms were examined combining a microsatellite analysis at mononucleotide locus BAT-26 and an
Publikováno v:
Diagnostic Molecular Pathology. 7:44-50
The expression of macrophage migration inhibitory factor (MIF) in prostate tissue was investigated by immunohistochemistry (IHC), enzyme-linked immunosorbent assay (ELISA), and Northern blot analysis using a prostate tissue bank. MIF expression was e
Publikováno v:
Diagnostic Molecular Pathology. 4:256-260
Alterations of p53 suppressor gene as a possible indicator of the metastatic potential of thyroid carcinomas were evaluated in a cohort of 45 thyroid carcinomas. Well-differentiated papillary and follicular carcinomas were evaluated; the poorly diffe
Autor:
Norihiro Kohara, Koichi Motojima, Junichiro Furui, Kunihide Izawa, Hiroshi Shiku, Takashi Kanematsu
Publikováno v:
Diagnostic Molecular Pathology. 3:184-191
The purpose of this study was to determine the correlation between expression of ras oncoproteins and the tumor stage or outcome of patients with gastric carcinoma. After the specificity of each anti-ras monoclonal antibody was confirmed by protein i