Zobrazeno 1 - 10
of 10 327
pro vyhledávání: '"Diabetes Mellitus"'
Autor:
Madhu Khullar, Arasambattu Kannan Munirajan, Sathyamangala V Naga Prasad, Sudesh Ravi, Nitish R. Mahapatra, Durairajpandian Vishnuprabu, Ajit S. Mullasari, Bhavani S. Sahu, Marimuthu S Ravi, Sanjib Senapati, Viswanathan Mohan, Richa Garg, Jiaur R. Gayen, Venkatesan Radha, Venkat R. Chirasani, Saurabh Sharma, Dhanya R Iyer, Malapaka Kiranmayi, Lakshmi Subramanian, Prasanna K.R. Allu, Sakthisree Maghajoti, Sromona D Mukherjee
Publikováno v:
Diabetes. 71:538-553
Pancreastatin (PST), a chromogranin A (CHGA)-derived potent physiological dysglycemic peptide, regulates glucose/insulin homeostasis. We have identified a non-synonymous functional PST variant (p.Gly297Ser; rs9658664) that occurs in a large section o
Publikováno v:
Diabetes. 71:530-537
At present, outside of infancy, genetic testing for monogenic diabetes is typically for mutations in maturity-onset diabetes of the young (MODY) genes that predominantly result in isolated diabetes. Monogenic diabetes syndromes are usually only teste
Publikováno v:
Diabetes
The coronavirus disease 2019 (COVID-19) global pandemic continues to spread worldwide with approximately 216 million confirmed cases and 4.49 million deaths to date. Intensive efforts are ongoing to combat this disease by suppressing viral transmissi
Publikováno v:
Diabetes
Type 2 diabetes (T2D) is a growing cause of poor health, psychosocial burden, and economic costs worldwide. The pancreatic β-cell is a cornerstone of metabolic physiology. Insulin deficiency leads to hyperglycemia, which was fatal before the availab
Autor:
Jihoon Shin, Michio Otsuki, Atsunori Fukuhara, Shigeki Nishitani, Iichiro Shimomura, Shunbun Kita, Shinichiro Toyoda
Publikováno v:
Diabetes
Aging, obesity, and diabetes are major risk factors for the severe progression and outcome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease 2019 [COVID-19]), but the underlying mechanism is not yet fully
Autor:
M. Arthur Charles, R. David G. Leslie
Publikováno v:
Diabetes
As the world endures a viral pandemic superimposed on a diabetes pandemic, the latter incorporates most of the comorbidities associated with the former, thereby exacerbating risk of death in both. An essential approach to both pandemics is prevention
Autor:
Martin Hrabé de Angelis, Rainer Lehmann, Norbert Stefan, Jürgen Machann, Hans Hauner, Stefan Kabisch, Peter Schwarz, Michael Roden, Fritz Schick, Stefan R. Bornstein, Kostantinos Kantartzis, Andreas L. Birkenfeld, Louise Fritsche, Andreas Peter, Andreas Fritsche, Corinna Dannecker, Stefan Kopf, Julia Clavel, Annette Schürmann, Martin Heni, Robert Wagner, Andreas Pfeiffer, Matthias Blüher, Vera Valenta, Katharina S. Weber, Andreas Lechner, Peter P. Nawroth, Hans-Ulrich Häring, Jochen Seißler, Renate Schick, Michael Stumvoll, Ulrike Dambeck, Michael Laxy, Karsten Müssig
Publikováno v:
Diabetes. 70:2785-2795
Lifestyle intervention (LI) can prevent type 2 diabetes, but response to LI varies depending on risk subphenotypes. We tested whether individuals with prediabetes with low risk (LR) benefit from conventional LI and individuals with high risk (HR) ben
Autor:
Young-Hoon Lee, Gi-Seok Park, Hyung-Bin Lim, Woo-Hyuk Lee, Jung Yeul Kim, Min Su Kim, Min-Woo Lee
Publikováno v:
Diabetes. 70:2663-2667
Type 2 diabetes mellitus (T2DM) and hypertension (HTN) are both relatively common systemic diseases and cause damage to the retina, such as inner retina reduction and microvascular impairment. The purpose of this study was to identify peripapillary r
Autor:
Ian Miao, Timothy J. Kieffer, Ann Y. Lee, Mojibian Majid, Shannon O'Dwyer, Maria M. Glavas, Fan Yang
Publikováno v:
Diabetes
We previously demonstrated that male, but not female, Swiss Webster mice are susceptible to diabetes, with incidence increased by early overnutrition and high-fat diet (HFD). In this study, we investigated how HFD in Swiss Webster males and females d
Autor:
Fiona M. Gribble, Robert Hansford, Maik Pietzner, Nicholas Bowker, A. Mesut Erzurumluoglu, Christopher N. Foley, Nicholas J. Wareham, Pallav Bhatnagar, Frank Reimann, Isobel D. Stewart, Eleanor Wheeler, Victoria P W Auyeung, Claudia Langenberg, Stephen Burgess, Matthew P. Coghlan
Publikováno v:
Diabetes
There is considerable interest in GIPR agonism to enhance the insulinotropic and extrapancreatic effects of GIP, thereby improving glycemic and weight control in type 2 diabetes (T2D) and obesity. Recent genetic epidemiological evidence has implicate