Zobrazeno 1 - 10
of 4 381
pro vyhledávání: '"Diabetes Mellitus"'
Autor:
Juhyun Kim, Aubrey Jensen, Seyoon Ko, Sridharan Raghavan, Lawrence S. Phillips, Adriana Hung, Yan Sun, Hua Zhou, Peter Reaven, Jin J. Zhou
Publikováno v:
Diabetes, vol 71, iss 5
Diabetes
Diabetes
Diabetes-related complications reflect longstanding damage to small and large vessels throughout the body. In addition to the duration of diabetes and poor glycemic control, genetic factors are important contributors to the variability in the develop
Publikováno v:
Diabetes. 71:530-537
At present, outside of infancy, genetic testing for monogenic diabetes is typically for mutations in maturity-onset diabetes of the young (MODY) genes that predominantly result in isolated diabetes. Monogenic diabetes syndromes are usually only teste
Autor:
Martin Hrabé de Angelis, Rainer Lehmann, Norbert Stefan, Jürgen Machann, Hans Hauner, Stefan Kabisch, Peter Schwarz, Michael Roden, Fritz Schick, Stefan R. Bornstein, Kostantinos Kantartzis, Andreas L. Birkenfeld, Louise Fritsche, Andreas Peter, Andreas Fritsche, Corinna Dannecker, Stefan Kopf, Julia Clavel, Annette Schürmann, Martin Heni, Robert Wagner, Andreas Pfeiffer, Matthias Blüher, Vera Valenta, Katharina S. Weber, Andreas Lechner, Peter P. Nawroth, Hans-Ulrich Häring, Jochen Seißler, Renate Schick, Michael Stumvoll, Ulrike Dambeck, Michael Laxy, Karsten Müssig
Publikováno v:
Diabetes. 70:2785-2795
Lifestyle intervention (LI) can prevent type 2 diabetes, but response to LI varies depending on risk subphenotypes. We tested whether individuals with prediabetes with low risk (LR) benefit from conventional LI and individuals with high risk (HR) ben
Autor:
Young-Hoon Lee, Gi-Seok Park, Hyung-Bin Lim, Woo-Hyuk Lee, Jung Yeul Kim, Min Su Kim, Min-Woo Lee
Publikováno v:
Diabetes. 70:2663-2667
Type 2 diabetes mellitus (T2DM) and hypertension (HTN) are both relatively common systemic diseases and cause damage to the retina, such as inner retina reduction and microvascular impairment. The purpose of this study was to identify peripapillary r
Autor:
Ian Miao, Timothy J. Kieffer, Ann Y. Lee, Mojibian Majid, Shannon O'Dwyer, Maria M. Glavas, Fan Yang
Publikováno v:
Diabetes
We previously demonstrated that male, but not female, Swiss Webster mice are susceptible to diabetes, with incidence increased by early overnutrition and high-fat diet (HFD). In this study, we investigated how HFD in Swiss Webster males and females d
Autor:
Fiona M. Gribble, Robert Hansford, Maik Pietzner, Nicholas Bowker, A. Mesut Erzurumluoglu, Christopher N. Foley, Nicholas J. Wareham, Pallav Bhatnagar, Frank Reimann, Isobel D. Stewart, Eleanor Wheeler, Victoria P W Auyeung, Claudia Langenberg, Stephen Burgess, Matthew P. Coghlan
Publikováno v:
Diabetes
There is considerable interest in GIPR agonism to enhance the insulinotropic and extrapancreatic effects of GIP, thereby improving glycemic and weight control in type 2 diabetes (T2D) and obesity. Recent genetic epidemiological evidence has implicate
Autor:
Lucas M. Wiggenhauser, Lena Metzger, Katrin Bennewitz, Silas Soleymani, Mike Boger, Christoph T. Tabler, Ingrid Hausser, Carsten Sticht, Paulus Wohlfart, Nadine Volk, Elena Heidenreich, Michael Buettner, Hans-Peter Hammes, Jens Kroll
Publikováno v:
Diabetes. 71:1073-1080
The pdx1−/− zebrafish mutant was recently established as a novel animal model of diabetic retinopathy. In this study, we investigate whether knockout of pdx1 also leads to diabetic kidney disease (DKD). pdx1−/− larvae exhibit several signs of
Autor:
Qianyi Yang, Jameson Hinkle, Jordan N. Reed, Redouane Aherrahrou, Zhiwen Xu, Thurl E. Harris, Erin J. Stephenson, Kiran Musunuru, Susanna R. Keller, Mete Civelek
Publikováno v:
Diabetes
Genome-wide association studies identified single nucleotide polymorphisms on chromosome 7 upstream of KLF14 to be associated with metabolic syndrome traits and increased risk for Type 2 Diabetes (T2D). The associations were more significant in women
Autor:
Kelly Rogers Keene, Farook Jahoor, Ruchi Gaba, Sanjeet Patel, Surya N. Mulukutla, Rasmus Bennet, Eunice I. Caducoy, Paras B. Mehta, Ashok Balasubramanyam, Åke Lernmark, W. Frank Peacock, Jean W. Hsu
Publikováno v:
Diabetes
When stable and near-normoglycemic, patients with “A−β+” ketosis-prone diabetes (KPD) manifest accelerated leucine catabolism and blunted ketone oxidation, which may underlie their proclivity to develop diabetic ketoacidosis (DKA). To understa
Autor:
Richard J MacIsaac, Jordan T. Kamel, Sabine Braat, Leslie Roberts, Laura E Downie, Jennifer P. Craig, Alexis Ceecee Britten-Jones
Publikováno v:
Diabetes. 70:1794-1806
This randomized, double-masked, placebo-controlled trial evaluated the effects of oral omega-3 (n-3) fatty acid supplementation on peripheral nerves in type 1 diabetes. Participants with type 1 diabetes were assigned (1:1) to n-3 (1,800 mg/day fish o