Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christie M. Ballantyne"'
Autor:
Jerry L. Perrard, Antu Kalathookunnel Antony, Huaizhu Wu, Christie M. Ballantyne, Zeqin Lian, Hua Liu, Lothar Hennighausen, Pradip K. Saha, Xiaoyuan Dai Perrard, Sean M. Hartig, Aaron R. Cox
Publikováno v:
Diabetes. 70:720-732
CD11c+ macrophages/dendritic cells (MDCs) are increased and display the classically activated M1-like phenotype in obese adipose tissue (AT) and may contribute to AT inflammation and insulin resistance. Stat1 is a key transcription factor for MDC pol
Publikováno v:
Diabetes. 70
Jak/STAT pathway plays key roles in inflammation and is highly activated in adipose tissue (AT) in obesity. Recently, inhibition of the Jak/STAT pathway with baricitinib, a Jak1/Jak2 inhibitor, has been demonstrated to accelerate clinical improvement
Autor:
Antu, Antony, Zeqin, Lian, Xiaoyuan Dai, Perrard, Jerry, Perrard, Hua, Liu, Aaron R, Cox, Pradip, Saha, Lothar, Hennighausen, Sean M, Hartig, Christie M, Ballantyne, Huaizhu, Wu
Publikováno v:
Diabetes
CD11c(+) macrophages/dendritic cells (MDCs) are increased and display the classically activated M1-like phenotype in obese adipose tissue (AT) and may contribute to AT inflammation and insulin resistance. Stat1 is a key transcription factor for MDC p
Publikováno v:
Diabetes. 69
Background: Aging (middle age) is usually associated with obesity and progressive low-grade inflammation in adipose tissue. However, how immune components in adipose tissue respond to aging is still not fully uncovered. Here, we sought to examine imm
Autor:
Lothar Hennighausen, Zeqin Lian, Jerry L. Perrard, Antu Kalathookunnel Antony, Christie M. Ballantyne, Huaizhu Wu, Clifton W. Smith, Xiaoyuan Dai Perrard
Publikováno v:
Diabetes. 67
Background: Obesity is a global epidemic and major risk factor for insulin resistance and type 2 diabetes. Obesity is associated with low grade chronic inflammation of adipose tissue (AT). F4/80+CD11c+ macrophages/dendritic cells are increased and po