Zobrazeno 1 - 10
of 31
pro vyhledávání: ''
Autor:
Bernd-Dieter Gonska
Publikováno v:
Der Klinikarzt. 42:116-121
The new ESC-Guidelines summarize the clinical and scientific results in the diagnosis and therapy of atrial fibrillation. The new oral anticoagulants have their place in the prevention of thromboembolic events. The new guidelines confirm the role of
Autor:
Christoph Bode, Martin Moser
Publikováno v:
Der Klinikarzt. 41:16-21
Safe and effective anticoagulation is a therapeutic cornerstone of thromboembolic diseases. Until recently oral vitamin K antagonists were the standard drugs for this indication. The new oral antagonists of the coagulation factors Xa (apixaban, rivar
Autor:
Hans-Ulrich Häring, Karsten Müssig
Publikováno v:
Der Klinikarzt. 40:286-289
Patienten mit Typ-2-Diabetes ebenso wie Menschen mit abnormer Glukosetoleranz weisen ein moderat erhohtes Krebsrisiko auf. Die bestehende Insulinresistenz mit kompensatorischer Hyperinsulinamie stellt einen wichtigen Faktor dar, der Krebs und metabol
Publikováno v:
Der Klinikarzt. 40:250-254
The field of COPD has faced several new and interesting developments in the past year. Predictions based on the updated BODE index match observed mortality better than before. Several studies suggest a susceptibility phenotype: frequent inflammatory
Autor:
Herbert Kuhnigk
Publikováno v:
Der Klinikarzt. 40:24-28
Autor:
Klaus Herrlinger, Klaus Fellermann
Publikováno v:
Der Klinikarzt. 39:84-89
Ulcerative colitis represents one of the main chronic inflammatory bowel diseases. This review highlights therapeutic principles according to the National (DGVS) and European (ECCO) guidelines. In general to date therapy relies on the suppression of
Autor:
Frank Mayer, Kathrin Rupertus
Publikováno v:
Der Klinikarzt. 39:18-22
In recent years, the inhibition of tumor angiogenesis has been established as a means of anti-tumor therapy. In colorectal and non-small cell lung cancer, the anti-VEGF antibody bevacizumab (avastin ® ) is approved for the treatment of metastatic di
Autor:
Katja Christina Weisel
Publikováno v:
Der Klinikarzt. 39:24-27
In hematologic malignancies, angiogenesis occurs within the bone marrow microenvironment comprised of various structures with complex interactions. Inhibition of angiogenesis therefore not only disrupts the oxygen and nutrient support of malignant ce
Publikováno v:
Der Klinikarzt. 38:438-442
Of superior importance for the novel concepts of activation of blood coagulation are the interactions of blood cells, the plasmatic coagulation factors and the dynamics of thrombin formation. A novel model of overlapping phases of activation and inte
Autor:
Job Harenberg
Publikováno v:
Der Klinikarzt. 38:443-451
Initial clinical trials have shown that new oral anticoagulants yield at least equal or even more effective and at least equally or better tolerated results than INR-adjusted coumarins. So far, data have been published for Dabigatran for atrial fibri