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Autor:
Colin McCarthy, Luca Ferrari, Hannah Fields, A Vitiello, Amber P. Sanchez, Franco Ferrari, Alison Tarke, Rafael Bejar, Tiffany N. Tanaka, Thomas A. Lane, Valentina Ferrari
Publikováno v:
Cytotherapy. 23:236-241
Background Myelodysplastic syndromes (MDS) represent the most common type of acquired bone marrow failure in adults and is characterized by ineffective maturation of myeloid precursor cells and peripheral cytopenias associated with higher rates of in
Autor:
Mao Pang, Limin Rong, Peigen Xie, Zihao Chen, Jian Mo, Yang Yang, Bin Liu, Qiyou Wang, Yuyong Chen, Jianwen Dong, Liangming Zhang, Zhongyu Liu, Cong Du, Nanxiang Wang
Publikováno v:
Cytotherapy. 23:57-64
Background aims Stem cell transplantation is a potential treatment for intractable spinal cord injury (SCI), and allogeneic human umbilical cord mesenchymal stem cells (hUC-MSCs) are a promising candidate because of the advantages of immune privilege
Autor:
Yao Wang, Kaichao Feng, Zhiqiang Wu, Fengxia Shi, Yang Liu, Qingming Yang, Yelei Guo, Hanren Dai, Weidong Han, Chuan Tong
Publikováno v:
Cytotherapy. 22:573-580
The current clinical outcome for patients with metastatic pancreatic carcinoma (PC) remains poor. Epidermal growth factor receptor (EGFR) is detectable in PC, suggesting that EGFR is a rational target in PC. We conducted a phase I clinical trial to e
Autor:
Tomoharu Miyashita, Sachiko Okada, Keiko Naitoh, Eri Oguma, Takashi Kamigaki, Kaori Makita, Hiroshi Ibe, Katsuro Tomita, Kosei Yasumoto, Shigenori Goto, Rishu Takimoto, Eishiro Mizukoshi
Publikováno v:
Cytotherapy. 22:329-336
Background aims Activated γδT cells have been shown to exhibit cytotoxicity against tumor cells. However, the efficacy of γδT cell immunotherapy for a large number of patients with solid tumors remains unclear. In this study, we examined the effi
Publikováno v:
Cytotherapy
Background This study examined the freezing responses of peripheral blood mononuclear cells (PBMCs) and specific white blood cell subsets contained therein when cryopreserved in three combinations of osmolytes composed of sugars, sugar alcohols and a
Autor:
Iben Spanggaard, Inge Marie Svane, Sine Reker Hadrup, Morten Hartvig Hansen, Vinicius Araujo Barbosa de Lima, Annie Borch, Arianna Draghi, Ulrik Lassen, Kristoffer Staal Rohrberg
Publikováno v:
Cytotherapy. 22:204-213
Background Immune checkpoint inhibitors (ICIs) have revolutionized the cancer therapeutic landscape and our perception of interactions between the immune system and tumor cells. Despite remarkable progress, disease relapse and primary resistance are
Autor:
Jiali Cheng, Li Zhu, Tongjuan Li, Lijun Jiang, Yaoyao Lou, Jue Wang, Xia Mao, Chunrui Li, Chen Zeng, Jianfeng Zhou, Liting Chen, Xiaoxi Zhou, Jin Huang
Publikováno v:
Cytotherapy. 22:166-171
Gastrointestinal (GI) tract is the most common site of extranodal involvement in non-Hodgkin lymphoma. Life-threatening complications of GI may occur because of tumor or chemotherapy. Chimeric antigen receptor (CAR) T-cell therapy has been successful
Publikováno v:
Cytotherapy. 22:16-20
Background aims Baseline platelet count has been shown to be a sensitive predictor of autologous peripheral blood progenitor cell collection yield in patients with multiple myeloma mobilized with granulocyte colony-stimulating factor (G-CSF). Patient
Autor:
Richard T. Maziarz, Peggy Appel, R. Knight, Rogelyn P. Kwock, Gabrielle Meyers, Laura F. Newell, Bryon Allen, Susan Slater, Brad Cota, Rachel J. Cook, Kelsea M. Shoop, Carol Jacoby, Casondra Ottowa, S. Murray
Publikováno v:
Cytotherapy
Introduction Published guidelines recommend 6-7 days of G-CSF followed by peripheral blood progenitor cell (PBPC) collection on day 5. Given successful PBPC collection occurs in some autologous transplants by day 4, and concern that a subset of healt
Autor:
Cecilia Fernández-Mateos, Mercedes Zurita, Estefanía García, Jesús Vaquero, Sara Fernández-Guinea, Jorge Mucientes, Maria L. Pascual
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
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After recent observations that intrathecal administration of autologous bone marrow mesenchymal stromal cells (MSCs) increases cerebral metabolism in patients with severe traumatic brain injury (TBI), we examined this type of cell therapy in Alzheime