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Publikováno v:
Cytotherapy. 22:16-20
Background aims Baseline platelet count has been shown to be a sensitive predictor of autologous peripheral blood progenitor cell collection yield in patients with multiple myeloma mobilized with granulocyte colony-stimulating factor (G-CSF). Patient
Autor:
Richard T. Maziarz, Peggy Appel, R. Knight, Rogelyn P. Kwock, Gabrielle Meyers, Laura F. Newell, Bryon Allen, Susan Slater, Brad Cota, Rachel J. Cook, Kelsea M. Shoop, Carol Jacoby, Casondra Ottowa, S. Murray
Publikováno v:
Cytotherapy
Introduction Published guidelines recommend 6-7 days of G-CSF followed by peripheral blood progenitor cell (PBPC) collection on day 5. Given successful PBPC collection occurs in some autologous transplants by day 4, and concern that a subset of healt
Autor:
Massimo Martino, Francesca Ronco, Caterina Musolino, Roberta Fedele, Caterina Alati, Fortunato Morabito, Giuseppa Penna, Tiziana Moscato, Santo Neri, Massimo Gentile, Eugenio Piro, Iolanda Vincelli, Anna Grazia Recchia, Stefano Molica
Publikováno v:
Cytotherapy. 17:1485-1493
Background aims Filgrastim and lenograstim are the standard granulocyte colony-stimulating factor (G-CSF) agents for peripheral blood stem cell mobilization (PBSC) in patients who undergo autologous stem cell transplantation. Methods To assess whethe
Autor:
Øystein Bruserud, Håkon Reikvam, Aymen Bushra Ahmed, Kristin Paulsen Rye, Einar K. Kristoffersen, Elisabeth Ersvær, Kimberley Joanne Hatfield, Guro Kristin Melve, Tor Hervig
Publikováno v:
Cytotherapy. 20(5)
Background Peripheral blood stem cells from healthy donors mobilized by granulocyte colony-stimulating factor (G-CSF) and thereafter harvested by leukapheresis are commonly used for allogeneic stem cell transplantation. Methods Plasma levels of 38 so
Publikováno v:
Cytotherapy. 16:1584-1589
Background aims Stem cell collection can be a major component of overall cost of autologous stem cell transplantation (ASCT). Plerixafor is an effective agent for mobilization; however, it is often reserved for salvage therapy because of its high cos
Autor:
Cristina Motlló, Josep-Maria Ribera, Mireia Morgades, Christelle Ferra, Montserrat Batlle, Susana Vives, David Gallardo, Jordi Juncà, Juan-Manuel Sancho, Anna Ester, Ramon Guardia, Evarist Feliu, Joan-Ramon Grifols, Fuensanta Millá, Inés Rodríguez
Publikováno v:
Cytotherapy. 16:406-411
Background aims The increasing scarcity of young related donors has led to the use of older donors for related allogeneic hematopoietic stem cell transplantation (HSCT). This study analyzed the influence of age on the results of mobilization of perip
Autor:
Evarist Feliu, Jordi Juncà, Anna Ester, Joan-Ramon Grifols, Susana Vives, David Gallardo, Ramon Guardia, Christelle Ferra, Juan-Manuel Sancho, Mireia Morgades, Monsterrat Batlle, Josep-Maria Ribera, Fuensanta Millá
Publikováno v:
Cytotherapy. 14:823-829
Failure in mobilization of peripheral blood (PB) stem cells is a frequent reason for not performing hematopoietic stem cell transplantation (HSCT). Early identification of poor mobilizers could avoid repeated attempts at mobilization, with the admini
Autor:
Isabelle Hellwig, Patrick Wuchter, Thomas Bruckner, Anthony D. Ho, Isabel Taubert, Rainer Saffrich, Abraham Zepeda-Moreno, Volker Eckstein
Publikováno v:
Cytotherapy. 13:459-466
Background aims. Previous studies have demonstrated that the combination of granulocyte – colony-stimulating factor (G-CSF) plerixafor is more effi cient in mobilizing CD34 hematopoietic stem cells (HSC) into the peripheral blood than G-CSF alone.
Autor:
Christopher Mccoy, Athena Paulsen, Abba C. Zubair, Peter X Adams, Marco A. Costa, David L. Amrani, Masakazu Ishikawa, Sunita Malik
Publikováno v:
Cytotherapy. 12:178-189
The distinction between hematopoietic stem cells (HSC) and endothelial progenitor cells (EPC) is poorly defined. Co-expression of CD34 antigen with vascular endothelial growth factor (VEGF) receptor (VEGFR2) is currently used to define EPC ( 1 ).We e
Autor:
Ronan Le Bouar, Stéphanie Pasquet, H. Sovalat, Philippe Henon, Jean-Pierre Monassier, Ingo Brink, Yazid Arkam, Robert Dallemand, Nicolas Bischoff, Valérie Rimelen, Mario Ojeda-Uribe
Publikováno v:
Cytotherapy. 11:1002-1015
Starting from experimental data proposing hematopoietic stem cells as candidates for cardiac repair, we postulated that human peripheral blood (PB) CD34+ cells mobilized by hematopoietic growth-factor (G-CSF) would contain cell subpopulations capable