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Publikováno v:
Current Vascular Pharmacology. 11:544-563
Hypoxia can induce functional and structural vascular remodeling by changing the expression of trophic factors to promote homeostasis. While most experimental approaches have been focused on functional remodeling, structural remodeling can reflect ch
Autor:
Susanne Bährle, Gábor Szabó
Publikováno v:
Current Vascular Pharmacology. 3:215-220
Ischemia and reperfusion injury leads to a complex pathophysiological process, which in turn results in the generation of free radicals. Peroxynitrite, a highly reactive species causes DNA single strand breaks, which activates the nuclear enzyme, pol
Publikováno v:
Current Vascular Pharmacology. 2:363-370
Elevated low density lipoprotein (LDL) cholesterol (LDL-C) levels represent one of the most important risk factors for atherosclerosis and therefore cardiovascular morbidity and mortality. LDL-C operates at different levels and through various classi