Zobrazeno 101 - 110
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Autor:
Hitoshi Okada, Petra Wülfroth, Satoshi Fujii, Steven L. Brown, Boris Vinogradsky, Craig H. Lundgren
Publikováno v:
Current Therapeutic Research. 57:192-202
The effect of etofibrate and nicanartine on plasminogen activator inhibitor type-1 (PAI-1) production in vitro and on plasma PAI-1 activity in vivo was determined. Both agents decreased baseline and transforming growth factor-β induced—PAI-1 synth
Autor:
Thomas Haak, Gerd Oremek, Karen Nelson, Daniel M. Kirsten, Matti Verho, Klaus-Henning Usadel, Kai Ihnken, Claudius Malerczyk, Winkelmann Br
Publikováno v:
Current Therapeutic Research. 57:88-102
We studied the effects of the angiotensin-converting enzyme inhibitor ramipril on plasma levels of adrenocorticotropic hormone (ACTH), cortisol, glucose, insulin, and C-peptide in patients with coronary artery disease. Patients were randomly assigned
Publikováno v:
Current Therapeutic Research. 57:42-47
We studied the effects of simvastatin treatment on plasma cholesterylester transfer protein (CETP) activity and lipid levels in patients with type IIa hypercholesterolemia. We treated 24 patients, 4 men and 20 women aged 49 to 81 years (mean age, 64.
Publikováno v:
Current Therapeutic Research. 57:26-32
Our study goal was to determine whether two hypolipidemic drugs, each with a different mechanism of action, have different effects on serum levels of high-density lipoprotein (HDL) subpopulations, as defined by the presence of apolipoprotein (apo) A-
Publikováno v:
Current Therapeutic Research. 57:797-809
The primary objective of this study was to compare the therapeutic effect of low-dose levosulpiride with pimozide in a representative sample of patients with negative symptoms of schizophrenia. As a secondary objective, possible synergism between hal
Autor:
Paulo Hilário Nascimento Saldiva, Geraldo S. Hidalgo, Elizabeth Brenda, Saul Goldenberg, Américo Marques
Publikováno v:
Current Therapeutic Research. 56:1285-1297
Four topical drugs were studied with regard to their ability to promote healing of open wounds in 60 Wistar rats. Five study groups were defined. Four of the five groups received one of the following substances: papain, sugar, minoxidil, or glucan. T
Publikováno v:
Current Therapeutic Research. 56:1202-1208
The US Pharmacopeia XXII standard test method was used to measure the defoaming properties of simethicone antacid products. It was found that two pharmaceutical products did not meet the standards. Differences in defoaming activity were found when a
Autor:
Sayuri Okushin, Takahiko Ogawa, Michio Yamakido, Naoki Hamaguchi, Hiroaki Oda, Akira Hirabayashi, Noriaki Yorioka, Kenichiro Shigemoto, Yoshihiko Taniguchi
Publikováno v:
Current Therapeutic Research. 56:1210-1220
Pravastatin was administered at a dosage of 10 mg/d for 24 weeks to 21 outpatients with glomerulonephritis with accompanying hyperlipidemia who presented with total serum cholesterol levels of ≥220 mg/dL. As a result, significant reductions in tota
Publikováno v:
Current Therapeutic Research. 56:1033-1040
We compared the effects of 600 mg of gemfibrozil twice daily (BID) and 900 mg of gemfibrozil once daily (OD) on lipid and glucose levels in 32 Chinese patients (13 men, 19 women) with non—insulin-dependent diabetes mellitus (NIDDM) using a crossove
Autor:
Stefano Ottolini, Danilo Conti, Elisabetta Ravera, Franco Maraffi, Edoardo Baggio, Claudio Montalto, Renato Gandini
Publikováno v:
Current Therapeutic Research. 56:1050-1058
Fifty-three patients with non—insulin-dependent diabetes mellitus and hypertension were randomly treated with extended-release felodipine 10 mg/d, amlodipine 10 mg/d, or placebo for 6 weeks. Mean clinostatic systolic and diastolic blood pressures w