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of 11
pro vyhledávání: ''
Autor:
Zurina Cinza Estévez, Elena Ferrer, Zaily Dorta Guridi, Santiago Dueñas-Carrera, Marlen Ivón Castellanos Fernández, Gillian Martínez Donato, Sacha Lazo del Vallín, Enrique Arús Soler, Carmen Valenzuela Silva, Lisset González Fabián, Liz Alvarez-Lajonchere
Publikováno v:
Current Therapeutic Research, Clinical and Experimental
Current Therapeutic Research, Vol 85, Iss C, Pp 20-28 (2017)
Current Therapeutic Research, Vol 85, Iss C, Pp 20-28 (2017)
Background An estimated 170 million individuals worldwide are infected with the hepatitis C virus (HCV). Although treatment options using a combination of pegylated interferon and ribavirin (P-IFN/RBV) are available, sustained clearance of the virus
Publikováno v:
Current Therapeutic Research, Vol 77, Iss C, Pp 73-78 (2015)
Current Therapeutic Research, Clinical and Experimental
Current Therapeutic Research, Clinical and Experimental
Background: Severe destructive hepatic injuries can be induced by acetaminophen overdose and may lead to acute hepatic failure. Objective: To investigate the ameliorative effects of Arctium lappa root extract on acetaminophen-induced hepatotoxicity.
Publikováno v:
Current Therapeutic Research, Vol 77, Iss C, Pp 52-57 (2015)
Current Therapeutic Research, Clinical and Experimental
Current Therapeutic Research, Clinical and Experimental
Background: Pitavastatin is a newly developed 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor approved for the treatment of hyperlipidemia. Pharmacokinetic properties of pitavastatin have been studied previously. Objective: To investigate t
Publikováno v:
Current Therapeutic Research, Clinical and Experimental
Current Therapeutic Research, Vol 77, Iss C, Pp 99-104 (2015)
Current Therapeutic Research, Vol 77, Iss C, Pp 99-104 (2015)
Background VIBATIV is a once-daily, injectable lipoglycopeptide antibiotic approved in the U.S. for the treatment of hospital-acquired and ventilator-associated bacterial pneumonia (HABP/VABP) caused by susceptible isolates of Staphylococcus aureus w
Autor:
Christine Lam, Olesya M. Taylor
Publikováno v:
Current Therapeutic Research, Clinical and Experimental
Current Therapeutic Research, Vol 93, Iss, Pp 100596-(2020)
Current Therapeutic Research, Vol 93, Iss, Pp 100596-(2020)
Background The World Health Organization estimates that diabetes is the seventh leading cause of death. Uncontrolled diabetes may cause severe consequences such as cardiovascular (CV) events (myocardial infarction, stroke, or CV mortality), lower-ext
Publikováno v:
Current Therapeutic Research, Vol 76, Iss C, Pp 17-20 (2014)
Current Therapeutic Research, Clinical and Experimental
Current Therapeutic Research, Clinical and Experimental
Objective: We aimed to investigate how losartan exerts protective effects on human umbilical vein endothelial cell injury induced by small, dense, LDL (sLDL) cholesterol particles. Methods: sLDL cholesterol was isolated by a 2-steps method and the nu
Autor:
Troy C. Quigg, Anne T. Nguyen, Samir K. Gupta, David A. Flockhart, John T. Callaghan, Colleen K. Stevens, Ingrid F. Metzger, Zeruesenay Desta, Abdulateef O. Aregbe, Nancy Thong, Noam Epstein
Publikováno v:
Current Therapeutic Research, Clinical and Experimental
Current Therapeutic Research, Vol 76, Iss C, Pp 64-69 (2014)
Current Therapeutic Research, Vol 76, Iss C, Pp 64-69 (2014)
Background: Efavirenz exhibits multiple interactions with drug-metabolizing enzymes and transporters, and for this reason efavirenz-based HIV therapy is associated with altered pharmacokinetics of coadministered drugs. Probably by the same mechanism,
Publikováno v:
Current Therapeutic Research, Vol 76, Iss C, Pp 126-133 (2014)
Current Therapeutic Research, Clinical and Experimental
Current Therapeutic Research, Clinical and Experimental
Background: Nonsteroidal anti-inflammatory drugs are the first-line option for treating ankylosing spondylitis (AS) in China. However, no large-scale controlled trials have been conducted in this ethnic population. Objective: To evaluate the efficacy
Autor:
Mariko Higa, Tetsuo Nishikawa, Yuya Tsurutani, Yoko Matsuzawa, Jun Saito, Matsuo Taniyama, Masao Omura
Publikováno v:
Current Therapeutic Research, Vol 84, Iss C, Pp 26-31 (2017)
Current Therapeutic Research, Clinical and Experimental
Current Therapeutic Research, Clinical and Experimental
Background: Sitagliptin, a dipeptidyl peptidase-4 inhibitor, is widely used in patients with type 2 diabetes. However, the pleiotropic effects of sitagliptin is not well understood. Objective: To assess the clinical efficacy and safety of sitagliptin
Autor:
Hideki Ishikawa, Masaki Kitajima, Motohide Shimazu, Koichiro Kumai, Yoshihide Otani, Naoki Aikawa, Masashi Yoshida, Tetsuro Kubota, Go Wakabayashi
Publikováno v:
Current Therapeutic Research, Vol 65, Iss 4, Pp 373-382 (2004)
Background: We have reported the preventive effect of cimetidine, a histamine type 2 receptor antagonist, on decreased gastric mucosal blood flow induced by burn injury, a model of surgical stress. Objective: The present study was performed to assess