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pro vyhledávání: '"Mandy L. Ford"'
Autor:
Pamela D. Winterberg, Mandy L. Ford
Publikováno v:
Current Opinion in Organ Transplantation. 22:22-28
Purpose of review Altered differentiation and activation of T-cell subsets occur in patients with chronic kidney disease (CKD), but the impact on graft rejection and protective immunity during transplantation are not fully understood. Recent findings
Autor:
Mandy L. Ford, Scott M. Krummey
Publikováno v:
Current Opinion in Organ Transplantation. 20:43-48
Stimulatory and inhibitory receptor signaling (cosignaling) on T cells is a critical component of T-cell responses that mediate graft rejection. The blockade of cosignaling pathways is an attractive strategy for preventing allogeneic T-cell responses
Autor:
I. Raul Badell, Mandy L. Ford
Publikováno v:
Current opinion in organ transplantation. 21(1)
PURPOSE OF REVIEW T follicular helper (Tfh) cells are an increasingly relevant CD4 T cell subset responsible for the provision of help to B cells for the generation of an effective humoral immune response. Here we review recent studies that have prov
Autor:
Mandy L. Ford, Christian P. Larsen
Publikováno v:
Current Opinion in Organ Transplantation. 15:405-410
This review highlights recent advances in our understanding of the frequency and nature of alloreactivity among memory T-cell populations, and discusses recent successes in experimentally targeting these populations in order to prolong graft survival