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Autor:
Wulf Paschen
Publikováno v:
Current Neurovascular Research. 1:173-181
The endoplasmic reticulum (ER) is a subcellular compartment playing a central role in folding and processing membrane and secretory proteins. The importance of these reactions for normal cellular function is indicated by the fact that blocking of the
Autor:
David S. Latchman
Publikováno v:
Current Neurovascular Research. 1:21-27
The heat shock proteins (hsps) are expressed in normal cells but their expression is enhanced by a number of different stresses including heat and ischemia. They play important roles in chaperoning the folding of other proteins and in protein degrada