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Autor:
Liu Handong, Hu Keqi
Publikováno v:
Current Cancer Drug Targets. 21:526-535
Background: The role and mechanism of long non-coding RNA cytoskeleton regulator (CYTOR) in Invasive Pituitary Adenomas (IPA) have not been elucidated previously. Objective: This study aimed to investigate the interaction between CYTOR and miR-206 an
Autor:
Jian Cao, Alex Helkin, Hoang-Lan Nguyen, Stanley Zucker, Kevin Cao, Qian Zhang, Song Wu, Pournima Kadam, Ghassan J. Samara
Publikováno v:
Current Cancer Drug Targets. 16:618-630
Membrane type 1-matrix metalloproteinase (MT1-MMP, MMP-14) is associated with cancer invasion and metastasis leading to poor patient prognosis. MT1-MMP mediates cancer cell invasion via degradation of basement membrane and extracellular matrix, and i
Autor:
Yang Cui, Ying Wang, Karin Wurtz, Hui Wang, Cheng Luo, Yan Li, Jiankang Liu, Jiangang Long, Zhihui Feng, Peter Weber, Hua Li, Yuan Li
Publikováno v:
Current Cancer Drug Targets. 13:625-639
Hydroxytyrosol, an important polyphenolic compound found in olive oil, has shown anti-tumor activity both in vitro and in vivo. However, effects of hydroxytyrosol on prostate cancer are largely unkown. We found that hydroxytyrosol preferentially redu
Publikováno v:
ResearcherID
Targets for cancer therapy are conventionally selected by identification of molecules acting downstream of established tumour suppressors and oncoproteins, such as p53, c-Myc and Ras. However, the forward genetics approach provides an alternative, co
Autor:
Brooks J, Sakina E. Eltom
Publikováno v:
Current Cancer Drug Targets. 11:654-669
The aryl hydrocarbon receptor (AhR) is a ligand activated basic helix-loop-helix transcription factor that binds to environmental poly aromatic hydrocarbons (PAH) and mediates their toxic and carcinogenic responses. There is ample documentation for t
Publikováno v:
Current Cancer Drug Targets. 10:307-318
The induction of G(1) cell cycle arrest and apoptosis by second-generation selenium compounds (e.g., methylselenol precursors such as methylseleninic acid, MSeA) may contribute to their anti-cancer activities. We have documented previously induction