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Autor:
Arthur F. Kramer, Chaeryon Kang, Edward McAuley, Chelsea M. Stillman, Patrick T. Donahue, Kirk I. Erickson, Charles H. Hillman, Jeffrey M. Burns, George A. Grove, Eric D. Vidoni
Publikováno v:
Contemp Clin Trials
Introduction Supervised exercise interventions are expensive and time intensive. However, there are financial costs to consider in addition to the intervention itself, namely: advertising and recruitment, outcome assessments, and other trial-related
Autor:
Paul A. Borsa, Steven Z. George, Margaret R. Wallace, Samuel S. Wu, Lauren N. Mackie, Roland Staud, Roger B. Fillingim, Warren H. Greenfield
Publikováno v:
Contemporary Clinical Trials. 56:9-17
Background Chronic musculoskeletal pain conditions are a prevalent and disabling problem. Preventing chronic musculoskeletal pain requires multifactorial treatment approaches that address its complex etiology. Prior cohort studies identified a high r
Autor:
Ronald C. Plotnikoff, Jordan J. Smith, Kristen E. Cohen, David R. Lubans, Magdalena Wilczynska, Sara L. Robards
Publikováno v:
Contemporary Clinical Trials. 49:116-125
Introduction The prevalence and risk of Type 2 Diabetes (T2D) has dramatically increased over the past decade. Physical activity (PA) has significant benefits for the treatment and prevention of T2D. The aim of this study is to develop, implement and
Autor:
Rowland W. Chang, Pamela A. Semanik, Linda Ehrlich-Jones, Jongmin Lee, Joe Feinglass, Dorothy D. Dunlop
Publikováno v:
Contemporary Clinical Trials. 39:224-235
Over 21 million Americans report an arthritis-attributable activity limitation. Knee osteoarthritis (OA) and rheumatoid arthritis (RA) are two of the most common/disabling forms of arthritis. Various forms of physical activity (PA) can improve a vari
Autor:
Elroy J. Aguiar, Philip J. Morgan, Ronald C. Plotnikoff, Myles D. Young, Clare E. Collins, Robin Callister
Publikováno v:
Contemporary Clinical Trials. 39:132-144
Background Intensive lifestyle interventions have been successful in reducing type 2 diabetes incidence. Whether intensive programmes requiring face-to-face contact, trained staff and access to facilities are feasible, on a larger scale, has been deb
Autor:
Megan B. Ratcliff, Richard F. Ittenbach, Cathleen Odar Stough, Christopher Bolling, Lisa M. Clifford, Stacey L. Simon, Mary Beth McCullough, Cynthia Zion, Shannon L. Robson, Lori J. Stark, Jessica C. Kichler, Stephanie S. Filigno
Publikováno v:
Contemporary clinical trials. 52
Obesity affects nearly 2 million preschool age children in the United States and is not abating. However, research on interventions for already obese preschoolers is limited. To address this significant gap in the literature, we developed an interven
Publikováno v:
Contemporary clinical trials. 41
Background This randomized controlled trial (RCT) will investigate the effects of a home-based aerobic exercise training regimen (i.e., cycle ergometry) on subclinical atherosclerosis and walking mobility in persons with multiple sclerosis (MS) and m
Autor:
Bernadette O. Fernandez, Martin Feelisch, Alexandra Cobb, Paula Meale, Edward Gilbert-Kawai, Maryam Khosravi, M. G. Mythen, Michael P.W. Grocott, Kay Mitchell, Daniel Martin, Denny Z. H. Levett
Publikováno v:
Contemporary clinical trials. 36(2)
The study of healthy human volunteers ascending to high altitude provides a robust model of the complex physiological interplay that emulates human adaptation to hypoxaemia in clinical conditions. Nitric oxide (NO) metabolism may play an important ro
Autor:
Bernardine M. Pinto, Jessica A. Whiteley, John M. Jakicic, Beth C. Bock, Bess H. Marcus, Beth A. Lewis, Abby C. King, Melissa A. Napolitano, Christopher A. Sciamanna, George D. Papandonatos, Alfred F. Parisi, Anna E. Albrecht
Publikováno v:
Contemporary clinical trials. 28(1)
Background Project STRIDE is a 4-year randomized controlled trial comparing two computer-based expert system guided intervention delivery channels (phone vs. print) for physical activity adoption and short-term maintenance among previously sedentary
Autor:
Anna E. Albrecht, Beth C. Bock, Melissa A. Napolitano, Jessica A. Whiteley, Alfred F. Parisi, Bess H. Marcus, John M. Jakicic, Beth A. Lewis, David M. Williams, Joseph W. Hogan
Publikováno v:
Contemporary clinical trials. 28(6)
Over two-thirds of Americans access the Internet and therefore, the Internet may be an important channel for reaching the large population of sedentary individuals. The purpose of this paper is to describe the methods for a randomized controlled tria