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An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2
Autor:
Jinrong Min, Li Li, Cheng Dong, Guangping Dong, Rong Huang, Yanli Liu, Licheng Zhu, Wolfram Tempel
Publikováno v:
Communications Biology
Communications Biology, Vol 1, Iss 1, Pp 1-9 (2018)
Communications Biology, Vol 1, Iss 1, Pp 1-9 (2018)
α-N-terminal methylation of proteins is an important post-translational modification that is catalyzed by two different N-terminal methyltransferases, namely NTMT1 and NTMT2. Previous studies have suggested that NTMT1 is a tri-methyltransferase, whe