Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Vipul Jairath"'
Publikováno v:
Cochrane Database Syst Rev
Background Medications used to treat inflammatory bowel disease (IBD) have significantly improved patient outcomes and delayed time to surgery. However, some of these therapies are recognized to increase the general risk of infection and have an uncl
Autor:
Mohamad Abbass, John K MacDonald, Cassandra M Townsend, Claire E Parker, Tran M Nguyen, Brian G. Feagan, Vipul Jairath, Jeremy Cepek, Reena Khanna
Publikováno v:
The Cochrane Library
Cochrane Database Syst Rev
Cochrane Database Syst Rev
BACKGROUND: Conventional medications for Crohn's disease (CD) include anti‐inflammatory drugs, immunosuppressants and corticosteroids. If an individual does not respond, or loses response to first‐line treatments, then biologic therapies such as
Autor:
John K MacDonald, Sarah C Davies, Reena Khanna, Vipul Jairath, Tran M Nguyen, Claire E Parker
Publikováno v:
Cochrane Database Syst Rev
The Cochrane Library
The Cochrane Library
BACKGROUND: Ustekinumab and briakinumab are monoclonal antibodies that target the standard p40 subunit of cytokines interleukin‐12 and interleukin‐23 (IL‐12/23p40), which are involved in the pathogenesis of Crohn's disease (CD). A significant p
Publikováno v:
The Cochrane Library
Background Patients with longstanding ulcerative colitis and colonic Crohn’s disease have an increased risk of colorectal cancer (CRC) compared with the general population. This review assessed the evidence that endoscopic surveillance may prolong
Autor:
Triana Lobaton, Jasvinder A. Singh, Reena Khanna, Tran M Nguyen, Sushil Kumar Garg, Brian G. Feagan, Vipul Jairath, Pieter Hindryckx, Orli M. Silverberg, Claire E Parker, GY Zou, Siddharth Singh
Publikováno v:
The Cochrane Library
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: We aim to conduct a systematic review and meta-analysis of all RCTs that compare biologic drugs (TNF-α antagonists, integrin antagonists, or ustekinumab) against
Autor:
Claire E Parker, John K MacDonald, Tran M Nguyen, Reena Khanna, Cassandra M Townsend, Brian G. Feagan, Vipul Jairath
Publikováno v:
The Cochrane Library
Background Several antibiotics have been evaluated in Crohn's disease (CD), however randomised controlled trials (RCTs) have produced conflicting results. Objectives To assess the efficacy and safety of antibiotics for induction and maintenance of re
Autor:
Brian G. Feagan, Reena Khanna, Navjot Deol, Vipul Jairath, Robert Battat, Claire E Parker, Tran M Nguyen
Publikováno v:
The Cochrane Library
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The primary aim of this systematic review is to determine the efficacy and safety of infliximab for maintaining remission in patients with CD.
Autor:
Ray Boyapati, Jean-Frederic Colombel, Brian G. Feagan, Reena Khanna, Carolina Palmela, Sonam D. Upadhyaya, Orli M. Silverberg, Claire E Parker, Vipul Jairath, Joana Torres
Publikováno v:
The Cochrane Library
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The primary objective of this review is to assess the feasibility and safety of discontinuing immunosuppressant or biologic drugs, administered alone or in combin
Autor:
Elizabeth Minas, Vipul Jairath, Omar Kherad, Sujata Biswas, Mark A Samaan, Geert D'Haens, Nathan S. S. Atkinson, Mohammad Al Beshir, Brian G. Feagan, Barrett G. Levesque, Claire E Parker, Daniël R. Hoekman, Majid A Almadi, Andreas Koutsoumpas, Reena Khanna, Thomas P. Chapman, Parambir S. Dulai, Turki AlAmeel, Simon Travis, William J. Sandborn, Guangyong Zou, Talal Al-Taweel, Sophie Restellini, Mark A. Glaire, Mahmoud Mosli, John K MacDonald
Publikováno v:
Cochrane Database of Systematic Reviews.
This is the protocol for a review and there is no abstract. The objectives are as follows: The objective of this review is to determine the factors that influence placebo response and remission rates in induction and maintenance trials of CD in which
Autor:
Reena, Khanna, Sigrid A, Nelson, Brian G, Feagan, Geert, D'Haens, William J, Sandborn, G Y, Zou, John K, MacDonald, Claire E, Parker, Vipul, Jairath, Barrett G, Levesque
Publikováno v:
Cochrane Database of Systematic Reviews. 2016
BACKGROUND: Endoscopic assessment of mucosal disease activity is widely used to determine eligibility and response to therapy in clinical trials of treatment for Crohn’s disease. However, the operating properties of the currently available endoscop