Zobrazeno 1 - 10
of 69
pro vyhledávání: ''
Publikováno v:
CNS Spectrums. 27:281-289
Hypoactive sexual desire disorder (HSDD) is a common female sexual dysfunction and is estimated to affect approximately 10% of women in the United States. It has been suggested that HSDD is associated with an imbalance of hormone and neurotransmitter
Publikováno v:
CNS Spectrums. 27:262-267
Aripiprazole lauroxil (AL) is a long-acting atypical antipsychotic approved for the treatment of schizophrenia in adults. AL has five regimen options that offer three different injection intervals using four different dosage strengths. The relationsh
Publikováno v:
CNS Spectrums. 26:625-636
BackgroundDepression is considered to be the most difficult to treat phase of bipolar disorder as patients experience residual symptoms causing long-term disability. This work aims to explore the role of add-on stimulant and stimulant-like medication
Autor:
Sergey Yagoda, Ying Jiang, Christina Arevalo, David McDonnell, Christine Graham, Adam Simmons
Publikováno v:
CNS Spectrums. 26:383-392
BackgroundCombination olanzapine and samidorphan (OLZ/SAM), in development for schizophrenia and bipolar I disorder, is intended to provide the efficacy of olanzapine while mitigating olanzapine-associated weight gain. OLZ/SAM safety, tolerability, a
Publikováno v:
CNS Spectrums. 25:493-501
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is characterized by deficits in social interactions and perseverative and stereotypical behavior. Growing evidence points toward a critical role for synaptic dysfunction in the onse
Publikováno v:
CNS Spectrums. 25:323-330
One of the challenges with initiating long-acting injectable (LAI) antipsychotic regimens is achieving relevant drug levels quickly. After first injection of the LAI antipsychotic aripiprazole lauroxil (AL), the lag to reaching relevant plasma aripip
Publikováno v:
CNS Spectrums. 25:343-351
Cariprazine is a new atypical antipsychotic drug (APD) with a unique pharmacodynamic profile, different from both typical and atypical APDs. Specifically, cariprazine acts as a partial agonist at the dopamine (DA) D2and D3receptors and serotonin 5-HT
Autor:
Davidd McDonnell, Ying Jiang, Bernard L. Silverman, Vasudev Bhupathi, Bei Yu, Craig Hopkinson, René S. Kahn, Lauren DiPetrillo, Adam Simmons, Jiani Yin, Christine Graham
Publikováno v:
CNS Spectrums. 26:155-156
ObjectiveCombination olanzapine and samidorphan (OLZ/SAM) is in development for treatment of schizophrenia and bipolar I disorder and is intended to provide the antipsychotic efficacy of olanzapine while mitigating olanzapine-associated weight gain.
Autor:
Laura von Hardenberg, Viktor B Nöhles, Katja Bödeker, Amanda Krogmann, Christoph U. Correll, Luisa Peters
Publikováno v:
CNS spectrums. 24(S1)
Schizophrenia remains one of the most severe medical diseases. Current dopamine modulating first-generation and second-generation antipsychotics target mainly positive symptoms, but not/inadequately negative and cognitive symptoms. Additional challen
Autor:
Leslie Citrome
Publikováno v:
CNS Spectrums. 23:355-357
Pimavanserin is not curative, but can improve the quality of life remaining for the person with Parkinson’s disease who typically has been suffering from this relentless neurodegenerative disease for years. Using pimavanserin effectively requires k