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Autor:
Yohei Masugi, Hirokazu Matsushita, Hiroaki Kuroda, Yusuke Takahashi, Takao Shigenobu, Ryutaro Hanawa, Atsushi Tajima
Publikováno v:
Clinical Lung Cancer. 22:e820-e828
Histologic subtyping offers some prognostic value in lung adenocarcinoma. We thus hypothesized that histologic subtypes may be useful for risk stratification of brain metastasis (BM). In this study, we aimed to investigate the impact of histologic su
Autor:
Peter J. Kneuertz, Morgan Fitzgerald, Desmond M. D’Souza, Mahmoud Abdel-Rasoul, Robert E. Merritt
Publikováno v:
Clinical Lung Cancer. 22:e574-e583
Background Stage I non–small-cell lung cancer (NSCLC) is potentially curable with surgical resection. Significant proportions of patients may still experience recurrence and death despite undergoing curative surgery. This study describes predictive
Autor:
Miyako Satouchi, Noriyuki Masuda, Toshinori Soejima, Hideyuki Harada, Masahiro Tanaka, Makoto Nishio, Isamu Okamoto, Takuyo Kozuka, Takashi Seto, Hiroshi Tsubouchi, Yasuyuki Kakurai, Koji Takeda, Tomonari Sasaki, Yasumasa Nishimura, Kazushige Hayakawa, Kazuhiko Nakagawa, Nobuyuki Yamamoto
Publikováno v:
Clinical Lung Cancer. 22:134-141
Background We evaluated the tolerability and efficacy of nimotuzumab, a humanized IgG1 monoclonal anti–epidermal growth factor receptor antibody, with concurrent chemoradiotherapy in patients with unresectable locally advanced non–small-cell lung
Autor:
Heung Tae Kim, Ji-Youn Han, Youngjoo Lee, Jin Soo Lee, Byung-Ho Nam, Hyae Young Kim, Hye Jin An, Geon Kook Lee
Publikováno v:
Clinical Lung Cancer. 21:e572-e582
Background We aimed to evaluate whether intercalated combination of EGFR tyrosine kinase inhibitor gefitinib and chemotherapy improves survival outcomes in never-smokers with advanced lung adenocarcinoma. Patients and Methods Never-smokers with chemo
Autor:
Akira Hamada, Shuta Ohara, Junichi Soh, Masato Chiba, Masaki Shimoji, Toshiki Takemoto, Kenichi Suda, Toshio Fujino, Tetsuya Mitsudomi
Publikováno v:
Clinical lung cancer. 23(1)
BACKGROUND The differential diagnosis of a solitary solid-type lung nodule is diverse. 18F-fluorodeoxyglucose positron emission tomography (PET) has a high sensitivity in the diagnosis of solid-type lung cancers; however, PET-negative, solid-type lun
Autor:
Francesco Guerrera, Guillaume Gauchotte, Lorenzo E. Ferri, Arthur Streit, Mathilde Prieto, Pierre-Emmanuel Falcoz, Joseph Seitlinger, Jonathan Spicer, Joëlle Siat, Stéphane Renaud, Gilbert Massard
Publikováno v:
Clinical lung cancer. 23(1)
Background : We sought to evaluate prognostic value of neutrophil-to-lymphocyte ratio (NLR) in surgically resected non-small cell lung cancer (NSCLC) and its correlation to oncogenic drivers. We retrospectively reviewed data of patients who underwent
Publikováno v:
Clinical Lung Cancer. 20:117-123
Background We sought reliable markers of survival and disease control among patients treated for limited-stage small-cell lung cancer (LS-SCLC). Patients and Methods Subjects were 122 patients given (chemo)radiotherapy for LS-SCLC at MD Anderson in 2
Autor:
Sonam Sharma, Christopher G. Berlind, Charles B. Simone, Melissa Culligan, William D. Lindsay, Vivek Verma, Christopher A. Ahern, Surbhi Grover, Jacob E. Shabason, Joseph S. Friedberg
Publikováno v:
Clinical Lung Cancer. 19:e901-e912
For the 3 histologic subtypes of malignant pleural mesothelioma (MPM)-epithelioid, sarcomatoid, and biphasic-the magnitude of benefit with surgical management remains underdefined.The National Cancer Data Base was queried for newly diagnosed nonmetas
A Phase II Clinical Trial of Apatinib in Pretreated Advanced Non-squamous Non–small-cell Lung Cancer
Autor:
Xiaoxia Chen, Anwen Xiong, Guanghui Gao, Shengxiang Ren, Jing Zhao, Weijing Cai, Caicun Zhou, Wei Li, Fengying Wu, Shijia Zhang, Chunxia Su, Fei Zhou
Publikováno v:
Clinical Lung Cancer. 19:e831-e842
Objectives Apatinib exhibits broad-spectrum antitumor activities by selectively inhibiting vascular endothelial growth factor receptor-2. This study evaluated the efficacy and safety of apatinib in patients with advanced non-squamous non–small-cell
Autor:
Ryoko Suzuki, Steven H. Lin, Xiong Wei, Ritsuko Komaki, Pamela K. Allen, James D. Cox, James W. Welsh
Publikováno v:
Clinical Lung Cancer. 19:e885-e891
Purpose Acute esophagitis is common after thoracic radiation therapy (TRT) given with chemotherapy for limited-stage small-cell lung cancer (LS SCLC). Although twice-daily TRT to 45 Gy in 30 fractions is considered standard, some clinicians are reluc