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Publikováno v:
Clinical Immunology and Immunopathology. 83:281-286
We investigated the changes in intracellular cytokine levels in different lymphocyte populations induced by measles virus (MV). MV-infected and uninfected peripheral blood mononuclear cells were cultured with phorbol 2-myristate 13-acetate plus ionom
Publikováno v:
Clinical Immunology and Immunopathology. 81:12-15
To evaluate the skin reactivity and the mast cell releasibility in the acquired immunodeficiency syndrome (AIDS), 24 patients with AIDS were skin tested with histamine (1 mg/ml) and codeine phosphate (0.9, 0.09, and 0.009 mg/ml), a mast cell degranul
Publikováno v:
Clinical Immunology and Immunopathology. 76:234-240
Vasculitis is an common clinical feature of systemic lupus erythematosus (SLE) in humans and in animal models of this disease. Humoral autoimmunity against endothelial cells has been previously demonstrated in SLE and other autoimmune disorders, but
Publikováno v:
Clinical Immunology and Immunopathology. 70:241-244
Serum analyses were performed regularly over 1 year of therapy with bioactive doses of recombinant interferon-gamma (mean 200 micrograms) in eight patients with advanced renal cell carcinoma in order to assess the usefulness of neopterin in monitorin
Autor:
John I. Gallin
Publikováno v:
Clinical Immunology and Immunopathology. 61:S100-S105
The bactericidal activity of phagocytic cells depends largely on the production of highly reactive metabolites from the metabolism of oxygen. A lesion anywhere in the biochemical pathway of hydrogen peroxide production has the potential to cause chro
Autor:
Wayland N. McKenzie, Ettayapuram V. Sunderrajan, Joram S. Seggev, Sheldon R. Braun, Frank X. O'Sullivan, Thomas Palomo, Sara E. Walker
Publikováno v:
Clinical Immunology and Immunopathology. 60:289-298
Estradiol (E) abolished clearing of pulmonary inflammation in 2-month-old male MRL/MpJ-lpr/lpr (MRL/l) mice treated with cyclophosphamide (CY). To determine if this effect persisted in animals with advanced disease, we studied male and female MRL/l m
Autor:
Janet L. Lathey, Thomas S. Edgington, Susan A. Gregory, Michael B. A. Oldstone, Jan M. Agosti, James H. Morrissey, Lawrence Corey, Jay A. Nelson
Publikováno v:
Clinical Immunology and Immunopathology. 54:1-13
Expression of tumor necrosis factor (TNF alpha), tissue factor (TF), and interleukin 1-beta (IL-1 beta) mRNA was evaluated in monocytes isolated from patients infected with human immunodeficiency virus (HIV). There was a significant depression (66%)
Autor:
Giuseppe Caramia, Giuseppina Di Stefano, Nicola Fabris, Anna Nobilini, A Tibaldi, Mauro Provinciali, Eugenio Mocchegiani, Lory Santarelli
Publikováno v:
Europe PubMed Central
An altered cellular immune response as a secondary phenomenon has been suggested to be probably involved in the bronchopulmonary infections by Pseudomonas aeruginosa in cystic fibrosis (CF). The difficulty to eradicate with modern anti-pseudomonal an
Publikováno v:
Clinical immunology and immunopathology. 73(2)
Human intravenous immunoglobulin (hIVIG) modifies the course of numerous immune-mediated diseases, but its specific mode of action remains unknown. In order to delineate possible immunoregulatory mechanisms, we studied the effects of hIVIG on the in
Monocyte culture and adherence modifies LPS-induced IL-6 production and inhibition by hydrocortisone
Publikováno v:
Clinical immunology and immunopathology. 72(2)
The effect of hydrocortisone (HC) on IL-6 production by monocytes (Mo) that were cultured under either adherent or limited-adherent culture conditions was determined. Although freshly isolated Mo produced more IL-6 in response to LPS than Mo cultured