Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Lipids"'
Publikováno v:
Clinical chemistry [Clin Chem] 1984 Mar; Vol. 30 (3), pp. 404-6.
Autor:
Bernd Genser, Marcus E. Kleber, Winfried März, Wolfgang Koenig, Günther Silbernagel, Hubert Scharnagl, Graciela E. Delgado, Andreas Ritsch, Volker Pfahlert, Haruna Ohrui, Tanja B. Grammer, Philipp Pagel
Publikováno v:
Clinical Chemistry. 63:1886-1896
BACKGROUNDThe inverse relationship between HDL cholesterol and cardiovascular mortality is weakened in coronary artery disease (CAD). We aimed to investigate the associations of HDL particle concentrations with cardiovascular mortality and the impact
Autor:
Henning Witt, Dietrich Rein, Matthias Lutz, Oliver J. Müller, Hugo A. Katus, Elvis Tahirovic, Erik Peter, Philipp Ternes, Philipp Schatz, Hans-Dirk Düngen, Evangelos Giannitsis, Norbert Frey, Michael Kreuter, Tanja Weis, Felix J.F. Herth, Susan Carvalho, Matthias Mueller-Hennessen, Tobias Daniel Trippel, Johanna Sigl
Publikováno v:
Clinical Chemistry. 63:267-277
OBJECTIVES In this study we aimed to identify novel metabolomic biomarkers suitable for improved diagnosis of heart failure with reduced ejection fraction (HFrEF). METHODS We prospectively recruited 887 individuals consisting of HFrEF patients with e
Autor:
Michelle Nieuwesteeg, Joshua E. Raizman, Khosrow Adeli, Yunqi Chen, David Blais, Victoria Higgins, Suzy L Wong
Publikováno v:
Clinical Chemistry. 61:1049-1062
BACKGROUND Biological covariates such as age and sex can markedly influence biochemical marker reference values, but no comprehensive study has examined such changes across pediatric, adult, and geriatric ages. The Canadian Health Measures Survey (CH
Autor:
Arnold J. J. Reuser, Juna M. de Vries, J. G. M. Huijmans, Daphne A. Goudriaan, Wim Sluiter, Jeroen C. van den Bosch, Carin M. van Gelder, Ans T. van der Ploeg, George J. G. Ruijter
Publikováno v:
Clinical Chemistry, 58(7), 1139-1147. American Association for Clinical Chemistry Inc.
Clinical Chemistry; Vol 58
Clinical Chemistry; Vol 58
BACKGROUNDUrinary excretion of the tetrasaccharide 6-α-D-glucopyranosyl-maltotriose (Glc4) is increased in various clinical conditions associated with increased turnover or storage of glycogen, making Glc4 a potential biomarker for glycogen storage
Autor:
Iman Sadri, Liam R. Brunham, Isabelle Ruel, Jean Bergeron, G.B. John Mancini, Arnold Ryomoto, Patrick Couture, Diane Brisson, Gordon A. Francis, Eric Wanneh, Robert Dufour, Robert A. Hegele, James M. Brophy, Daniel Gaudet, Sumayah Aljenedil, Alexis Baass, Émilie de Varennes, Jacques Genest, Lubomira Cermakova
Publikováno v:
Clinical chemistry. 64(2)
BACKGROUND Familial hypercholesterolemia (FH) is the most frequent genetic disorder seen clinically and is characterized by increased LDL cholesterol (LDL-C) (>95th percentile), family history of increased LDL-C, premature atherosclerotic cardiovascu
Autor:
Joshua W. Knowles, Erik Ingelsson
Publikováno v:
Clinical chemistry. 63(7)
Low-density lipoprotein cholesterol (LDL-C)-lowering alleles in or near NPC1L1 or HMGCR, encoding the respective molecular targets of ezetimibe and statins, have previously been used as proxies to study the efficacy of these lipid-lowering drugs. All
Publikováno v:
Clinical Chemistry. 51:1201-1205
Background: Epidemiologists have observed that blood donation is associated with decreased risk of type 2 diabetes and cardiovascular disease. Methods: We investigated the relationship between iron stores and insulin sensitivity, after controlling fo
Autor:
Tormod Fladby, Inge Grundke-Iqbal, Khalid Iqbal, Kaj Blennow, Henrik Zetterberg, Sonia Chalbot
Publikováno v:
Clinical Chemistry. 55:2171-2179
Background: The phospholipase A2 (PLA2) family comprises multiple isoenzymes that vary in their physicochemical properties, cellular localizations, calcium sensitivities, and substrate specificities. Despite these differences, PLA2s share the ability
Autor:
Dick C. Chan, Kerry-Anne Rye, Gilles Lambert, Esther M.M. Ooi, Gerald F. Watts, P. Hugh R. Barrett
Publikováno v:
Clinical Chemistry. 55:2049-2052
Background: Experimental studies suggest that proprotein convertase subtilisin/kexin type 9 (PCSK9) is an important regulator of LDL metabolism because of its ability to facilitate degradation of the LDL receptor. We investigated the association betw