Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Andres J. Klein-Szanto"'
Autor:
Andres J. Klein-Szanto, Javier S. Castresana, Daniel E. Bassi, Gary Thomas, Ricardo Lopez de Cicco, Javier Mercapide
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(8)
Purpose: Astrocytoma arises in the central nervous system as a tumorof great lethality, in part because of the invasive potential of the neoplastic cells that are able to release extracellular matrix-degrading enzymes. Furin convertase activates seve
Autor:
Masahiko Tsujimoto, Ken-ichirou Morishige, Mareo Yamoto, Tadashi Kimura, Russell J. Schilder, Kenjiro Sawada, Chiaki Kawase, Joseph R. Testa, Masami Hayashi, Masahide Ohmichi, Andres J. Klein-Szanto, Seiji Mabuchi, Deborah A. Altomare
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 15(17)
Purpose: Mammalian target of rapamycin (mTOR) plays a central role in cell proliferation and is regarded as a promising target in cancer therapy, including for ovarian cancer. This study aimed to examine the role of mTOR as a therapeutic target in cl