Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Anne Berger"'
Autor:
Franck Zinzindohoué, Thierry Lecomte, Jean-Marc Ferraz, Anne-Marie Houllier, Paul-Henri Cugnenc, Anne Berger, Hélène Blons, Pierre Laurent-Puig
Publikováno v:
Clinical Cancer Research. 11:594-599
Purpose: Matrix metalloproteinase (MMP) belongs to a large group of proteases capable of breaking essentially all components of the extracellular matrix. They are implicated in all steps of tumorogenesis, cancer invasion, and metastasis. Among them,
Autor:
Anne Berger, Marie-Anne Loriot, Philippe Beaune, Franck Zinzindohoué, Thierry Lecomte, Jean-Marc Ferraz, Pierre Laurent-Puig, David-Alexandre Trégouët, Bruno Landi, Paul-Henri Cugnenc, Raymond Jian
Publikováno v:
Clinical Cancer Research. 10:5880-5888
Purpose: The target enzyme for 5-fluorouracil (5-FU) is thymidylate synthase (TS). The TYMS gene encoding this enzyme is polymorphic, having either double (2R) or tri-tandem (3R) repeats of a 28-bp sequence in the promoter region and a 6-bp variation