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pro vyhledávání: '"Rabia Hussain"'
Autor:
Sherin Zafar, Tom H. M. Ottenhoff, S. Brahmbhatt, Graham H. Bothamley, Rabia Hussain, Jan W. Drijfhout, F. V. Lopez, Hazel M. Dockrell, Ghaffar Dawood, Steven G. Smith
Publikováno v:
Clinical and Experimental Immunology. 128:140-148
SUMMARYIn order to identify T cell epitopes within the Mycobacterium leprae 45-kD serine-rich antigen, we analysed responses to overlapping 17-mer peptides encompassing the whole antigen in non-exposed UK controls, Pakistani leprosy patients and tube
Publikováno v:
Clinical and Experimental Immunology. 123:210-218
SUMMARYCachexia is one of the prominent features of advanced tuberculosis (TB) seen in association with increased expression of the monokine TNF-α. Several mycobacterial proteins, including PPD, stimulate TNF-α secretion from monocytes. Host factor
Publikováno v:
Clinical and Experimental Immunology. 114:204-209
SUMMARYT cell responses play a critical role in determining protective responses to leprosy. Patients with self-limiting tuberculoid leprosy show high T cell reactivity, while patients with disseminated lepromatous form of the disease show absent to