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Autor:
J. Perren Cobb, Lakshmi S. Parvathaneni, Virginie Bourlier, Craig Sauter, Walter A. Boyle, Victor E. Laubach
Publikováno v:
Circulation Research. 87
Abstract —Septic shock is characterized by vasodilation and decreased responsiveness to vasoconstrictors. Recent studies suggest this results from nitric oxide (NO) overproduction after expression of the calcium-independent isoform of NO synthase (