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Autor:
Anders Heiervang Tennøe, Cathrine Brunborg, Øyvind Midtvedt, Trond Mogens Aaløkken, Øyvind Molberg, Thor Ueland, Pål Aukrust, May Britt Lund, Anna-Maria Hoffmann-Vold, Torhild Garen, Aurelija Abraityte
Publikováno v:
Chest. 150:299-306
Markers for early identification of progressive interstitial lung disease (ILD) in systemic sclerosis (SSc) are in demand. Chemokine CCL18, which has been linked to pulmonary inflammation, is an interesting candidate, but data have not been consisten
Autor:
Thomas K. Waddell, Marco Mura, Shaf Keshavjee, Lianne G. Singer, Mingyao Liu, John Granton, Karen McRae, Masaki Anraku, Zhihong Yun, Marc de Perrot
Publikováno v:
Chest. 141:661-673
Background Pulmonary hypertension (PH) associated with pulmonary fibrosis (PF) is a severe condition with poor outcome. It is unknown whether patients with PF with associated PH (APH) represent a distinct phenotype of the disease. We hypothesized tha
Autor:
Olivier Sitbon, Marc Humbert, Eric Hachulla, Pierre-Yves Hatron, Gérald Simonneau, Alice Bérezné, Loïc Guillevin, Pierre Clerson, Luc Mouthon, David Launay
Publikováno v:
Chest. 136:1211-1219
Background Pulmonary arterial hypertension (PAH) is a frequent cause of morbidity and mortality in patients with systemic sclerosis (SSc). PAH is generally considered to be a late complication of limited cutaneous SSc. This study identified and inves
Autor:
Masanori Kitaichi, Shigeru Tanaka, Michiaki Mishima, Tomohiro Handa, Takateru Izumi, Taishi Nagao, Michio Shigematsu, Kunio Hamada, Sonoko Nagai
Publikováno v:
Chest. 131:650-656
To evaluate the long-term clinical course of patients with idiopathic pulmonary fibrosis (IPF) complicated with pulmonary arterial hypertension.Prospective analysis of consecutive IPF patients undergoing initial workup with right-heart catheterizatio
Prevalence and Outcomes of Pulmonary Arterial Hypertension in Advanced Idiopathic Pulmonary Fibrosis
Publikováno v:
Chest. 129:746-752
The development of pulmonary arterial hypertension (PAH) can complicate many interstitial lung diseases, including idiopathic pulmonary fibrosis (IPF). We sought to characterize the prevalence of PAH and its impact on survival in patients with advanc
Autor:
Marshall S. Riley, Janos Porszasz, Mariëlle P.K.J. Engelen, Karlman Wasserman, Bruce H. Brundage, Joe Miranda
Publikováno v:
Scopus-Elsevier
Nitric oxide (NO), a potent vasodilator, is present in the exhaled air of humans. We wished to quantify NO production in patients with abnormalities of the pulmonary circulation.Nine patients with primary pulmonary hypertension (PPH), six with pulmon
Publikováno v:
Chest. 102:1645-1650
We performed a morphometric analysis of peribronchiolar and perivascular fibrosis in lungs obtained at autopsy from six patients with chronic bronchitis, six with pulmonary emphysema, and four normal control subjects. The areas of fibrosis outside th
Autor:
Oksana A. Shlobin, Rajeev Saggar, Steven M. Kawut, Steven D. Nathan, Abbas Ardehali, John A. Belperio, Marvin I. Schwarz, Arun S. Karlamangla, David J. Ross, Joseph P. Lynch, David A. Zisman
Publikováno v:
Chest. 133(3)
We have developed a method to screen for pulmonary hypertension (PH) in idiopathic pulmonary fibrosis (IPF) patients, based on a formula to predict mean pulmonary artery pressure (MPAP) from standard lung function measurements. The objective of this
Autor:
Wander de Oliveira Villalba, Percival D. Sampaio-Barros, Elza Maria Figueiras Pedreira de Cerqueira, Ilma Aparecida Paschoal, João Francisco Marques-Neto, Mônica Corso Pereira, Cid A. Leme
Publikováno v:
Chest. 131(1)
Pulmonary involvement is the leading cause of systemic sclerosis (SSc)-related deaths. A simple test to evaluate exercise capacity is the 6-min walk test (6MWT), and the walk distance is used as a primary outcome in clinical trials. Hemoglobin desatu
Publikováno v:
Chest. 113(3)
To determine the prevalence of right and left ventricular dysfunction in a prescreened population of patients with severe pulmonary disease, and to analyze the relationship between right and left ventricular function.Retrospective record review of 43