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Autor:
M. Patricia Rivera, James D. Luketich, Martin J. Edelman, Matthew J. Monberg, Frank C. Detterbeck, Mark A. Socinski, Richard J. Gralla, Guangbin Peng, Rafat Ansari, Dominic T. Moore, Coleman K. Obasaju, Thierry Jahan
Publikováno v:
Chest. 135:1588-1595
Several chemotherapy agents, including gemcitabine and paclitaxel, have been reported to cause interstitial pneumonitis. The incidence of pulmonary toxicity from the combination of gemcitabine and paclitaxel is reported to be approximately 5%. In thi
Autor:
Carolyn H. Welsh, Sujatha Hariharan
Publikováno v:
Chest. 131:1978-1981
Autor:
Yutaka Kubota, Taichiro Arimoto, Yoshinobu Iwasaki, Masaki Nakanishi, Atsushi Natuhara, Hiroshi Hara, Kazuhiro Nagata, Mikio Ueda
Publikováno v:
Chest. 128:2268-2273
Purpose To determine the tolerability and feasibility of double-cycle, high-dose chemotherapy followed by peripheral blood stem-cell transplantation (PBSCT) after conventional chemotherapy or chemoradiotherapy for small cell lung cancer (SCLC). Patie
Autor:
David N. Howell, R. Duane Davis, Scott M. Palmer, H. Page McAdams, B. Diane Reams, Mark P. Steele
Publikováno v:
Chest. 124:1242-1249
Introduction Posttransplant lymphoproliferative disorder (PTLD) is a relatively infrequent but devastating complication that occurs after solid-organ transplantation. Although the optimal treatment for this condition is unknown, rituximab, a murine/h
Autor:
Sanjay Kalra, Ulrich Specks, Zvezdana Vuk-Pavlovic, Darrell R. Schroeder, Andrew H. Limper, John P. Scott, James P. Utz
Publikováno v:
Chest. 124:177-185
Background Tumor necrosis factor (TNF)-α is produced by macrophages and other cells, and is believed to participate in granulomatous inflammation. Targeted antagonism of TNF-α has been proposed as a novel treatment strategy for sarcoidosis. Etanerc
Publikováno v:
Chest. 123:2150-2153
Methotrexate has proven to be effective in treating rheumatoid arthritis (RA), and is believed to be nononcogenic in the low weekly dose typically employed in the patients with RA. We report, however, a patient with RA in whom a rapidly enlarging dif
Autor:
Andreas Greinacher, P Eichler, Angelika Eichner, Lena E. Carlsson, Norbert Lubenow, Reiner Kempf
Publikováno v:
Chest. 122:37-42
Study objectives Heparin-induced thrombocytopenia (HIT) is an immune-mediated adverse drug reaction associated with a decrease of platelet counts that usually begins after at least 5 days of heparin treatment. Uncertainty exists about the risk of ear
Autor:
Chun-Ming Tsai, Yuh Min Chen, Jacqueline Whang-Peng, Reury Perng Perng, Tsang Wu Liu, Jacqueline Ming-Liu, Kuang Yao Yang
Publikováno v:
Chest. 117:1583-1589
Study objective: Vinorelbine and gemcitabine are two active single agents used in the treatment of non-small cell lung cancer (NSCLC). A clinical trial was conducted to evaluate the efficacy and toxicity of vinorelbine plus gemcitabine in patients wi
Publikováno v:
Chest. 116:566-569
A young woman with primary pulmonary hypertension presented with interstitial lung disease approximately 5 years after successful treatment with IV prostacyclin. The pathology was consistent with nonspecific interstitial pneumonitis and was unrespons
Autor:
Matthew G. Marin
Publikováno v:
Chest. 112:29-33
Study objectives To determine if treatment with low-dose methotrexate spares oral steroids in adult, steroid-dependent, asthmatic patients. Design Articles identified by computer search were excluded if they (1) did not contain original data relating