Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Hiroshi Sugiyama"'
Publikováno v:
Chemistry – A European Journal. 29
Förster resonance energy transfer (FRET) is an attractive tool for understanding biomolecular dynamics. FRET-based analysis of nucleosomes has the potential to fill the knowledge gaps between static structures and dynamic cellular behaviors. Compare
Publikováno v:
Chemistry – A European Journal. 27:778-784
Stimuli-responsive switching molecules have been widely investigated for the purpose of the mechanical control of biomolecules. Recently developed arylazopyrazole (AAP) shows photoisomerization activity, displaying a faster response to light-induced
Publikováno v:
Chemistry – A European Journal. 26:15282-15289
The nucleosome is one of the most fundamental units involved in gene expression and consequent cell development, differentiation, and expression of cell functions. We report here a method to place reconstituted nucleosomes into a DNA origami frame fo
Publikováno v:
Chemistry – A European Journal. 26:14639-14644
Many types of molecular targeted drugs that inhibit cancer growth by acting on specific molecules have been developed. The runt-related transcription factor (RUNX) family, which induces cancer development by binding to a specific DNA sequence, has at
Autor:
Tomoko Emura, Kumi Hidaka, Shengtao Yao, Yangyang Yang, Yufang Xu, Chunhai Fan, Rizhao Pan, Masayuki Endo, Shiwei Zhang, Xuhong Qian, Hiroshi Sugiyama
Publikováno v:
Chemistry – A European Journal. 25:5158-5162
Biological macromolecular machines perform impressive mechanical movements. F-adenosine triphosphate (ATP) synthase uses a proton gradient to generate ATP through mechanical rotations. Here, a programmed hexagonal DNA nanomachine, in which a three-ar
Autor:
Zutao Yu, Xiwen Xing, Fenyong Liu, Kumi Hidaka, Akira Ono, Yihong Feng, Masayuki Endo, Hiroshi Sugiyama
Publikováno v:
Chemistry - A European Journal. 25:1446-1450
This work demonstrates single-molecule imaging of metal-ion induced double-stranded DNA formation in DNA nanostructures. The formation of the metal ion-mediated base pairing in a DNA origami frame was examined using C-Ag-C and T-Hg-T metallo-base pai
Publikováno v:
Chemistry – A European Journal. 24:17091-17095
A distance- and orientation-factor-dependent FRET system is a useful and attractive approach to the investigation of the conformational dynamics of nucleosomes. In this study, the application of the highly emissive nucleobase th dG-tC FRET pair to 60
Autor:
Sefan Asamitsu, Hiroshi Sugiyama, Danith H. Ly, Zutao Yu, Toshikazu Bando, Kaori Hashiya, Wei-Che Hsieh
Publikováno v:
Chemistry
Synthetic molecules capable of DNA binding and mimicking cooperation of transcription factor (TF) pairs have long been considered a promising tool for manipulating gene expression. Our previously reported Pip-HoGu system, a programmable DNA binder py
Publikováno v:
Chemistry - A European Journal. 23:7607-7613
A new type of Forster Resonance Energy Transfer (FRET) system using highly emissive isomorphic nucleobase analogues is reported. The FRET pair consists of 2-aminothieno[3,4-d]pyrimidine G-mimic deoxyribonucleoside (th dG) as an energy donor and 1,3-d
Autor:
Yuki Suzuki, Tomoko Emura, Ryu Tashiro, Kumi Hidaka, Hiroshi Sugiyama, Masayuki Endo, Yangyang Yang
Publikováno v:
Chemistry - A European Journal. 23:3979-3985
Various DNA-based nanodevices have been developed on the nanometer scale using light as regulation input. However, the programmed controllability is still a major challenge for these artificial nanodevices. Herein, we demonstrate a rotary DNA nanostr