Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ah Young Park"'
Autor:
Won Hee Kim, Pusoon Chun, Hyung-Rock Lee, Ah-Young Park, Hyung Ryong Moon, Boeun Lee, Jungsu Kim, Jin-Ah Kang, Jin-Ah Kim, Lak Shin Jeong
Publikováno v:
ChemInform. 41
Autor:
Hyung Sik Kim, Jungsu Kim, Won Hee Kim, Jin-Ah Kang, Ping Gong, Lak Shin Jeong, Jin-Ah Kim, Zunhua Yang, Hyung Ryong Moon, Ah-Young Park
Publikováno v:
ChemInform. 40
Eleven novel oxiranyl and thiiranyl phenolic compounds were synthesized as potential antitumor agents using epichlorohydrin and epithiohydrin in the presence of K2CO3. Cytotoxicities were found in range of IC50 values of 2.5-14.8 µM, which was parti
Autor:
Hyung-Rock Lee, Pusoon Chun, Won Hee Kim, Hyung Ryong Moon, Lak Shin Jeong, Ah-Young Park, Kyung Ran Kim, Jang Ho Bae, Jin-Ah Kang
Publikováno v:
ChemInform. 40
Publikováno v:
ChemInform. 39
Novel l-bicyclocarba-d4T (1), an enantiomer of d-N-MCd4T has been enantiopurely synthesized as a potent anti-HIV agent starting from (R)-epichlorohydrin using tandem alkylation, chemoselective reduction of ester in the presence of lactone functional
Publikováno v:
ChemInform. 39
Pseudo-l-vinylcyclopropyl adenine and guanine nucleosides 11 and 12 were designed and enantiopurely synthesized starting from (S)-epichlorohydrin using tandem alkylation, regioselective oxirane-ring opening, and chemoselective reduction as key steps.
Publikováno v:
ChemInform. 39
Pseudo-d-vinylcyclopropyl nucleosides 10–12 bearing a quaternary carbon were designed and synthesized starting from (R)-epichlorohydrin using a tandem reaction of double alkylation and lactonization via oxirane-ring opening reaction, a Wittig react
Publikováno v:
ChemInform. 39
Publikováno v:
ChemInform. 39
Novel iso D-2',3'-dideoxythianucleoside derivatives 1-3 were designed and asymmetrically synthesized to search for new anti-HIV agents. Final compounds 1-3 were evaluated against a variety of viruses including HIV-1 and 2. Only cytosine analog 3 show
Publikováno v:
ChemInform. 38
L-N-MCd4T (1) has been synthesized as a potent anti-HIV agent starting from (R)-epichlorohydrin using tandem alkylation, chemoselective reduction of ester in the presence of lactone functional group, RCM reaction and Mitsunobu reaction as key steps a