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Autor:
Zahir A. Shaikh, J. Crispin Smith
Publikováno v:
Chemico-Biological Interactions. 19:161-171
The mechanisms by which cadmium (Cd) stimulates the synthesis of hepatic and renal metallothionein were investigated in rats. In the liver the incorporation of 35S and 14C labels from cystine showed a lag period of about 2 h and maximum incorporation
Autor:
J. Crispin Smith, Zahir A. Shaikh
Publikováno v:
Chemico-biological interactions. 15(4)
The biosynthesis of the cadmium-binding protein, metallothionein, was studied in rat liver and kidney after injection of cadmium chloride. A simplified procedure for the isolation of metallothionein from liver and kidney tissues was devised. It was f