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Publikováno v:
Chemico-Biological Interactions. 308:155-163
Chelidonium majus L. is a herbal medicine widely employed in Europe and Western Asia. Chelidonine (CHE) is a major constituent of the herb and has been reported to be an inhibitor of the cytochrome P450 enzymes (CYP). The major objective of the prese
Publikováno v:
Chemico-Biological Interactions. 279:196-202
In the present study we investigated the effects of Diphenyl Diselenide (DPDS) on behavioral and biochemical parameters in Drosophila melanogaster (DM). We also tried to explore the gender differences in response to DPDS treatment. One of the salient
Publikováno v:
Chemico-Biological Interactions. 273:142-153
HIV/AIDS patients have suppressed immune system, making them vulnerable to many opportunistic infections including tuberculosis (TB). The patients who are co-infected with TB undergo combined regimens with anti-retroviral drugs such as zidovudine (AZ
Autor:
Chi Mingwei, Nan Xie, David I. Leavesley, Yan Xie, Hui Zhou, Hong Zhang, Xingwang Deng, Qian Chen, Huijuan Shi, Yinxue Yang
Publikováno v:
Chemico-Biological Interactions. 271:59-66
Psoriasis vulgaris is a chronic inflammatory skin disease, stubbornly intractable, with substantial consequences for patient physical and mental welfare. Approaches currently available to treat psoriasis are not satisfactory due to undesirable side-e
Autor:
Chien-Ying Lee, Yi-Ching Li, Shiuan-Shinn Lee, Yu-Hsiang Kuan, Yung-Chyuan Ho, Ming-Ling Yang, Rosa Huang-Liu
Publikováno v:
Chemico-Biological Interactions. 271:9-14
Zerumbone, a cyclic eleven-membered sesquiterpene, is the major component of the essential oil isolated from the wild ginger, Zingiber zerumbet. There are several beneficial pharmacological activities of zerumbone including anti-inflammatory, antioxi
Publikováno v:
Chemico-Biological Interactions. 269:18-24
Demethoxyfumitremorgin C, a secondary metabolite of the marine fungus, Aspergillus fumigatus, had been reported to demonstrate cytotoxic effect on mouse tsFT210 cells. However, no information is available regarding its functional mechanism and the ch
Autor:
Glaucilane dos Santos Cruz, Mariana Oliveira Breda, Carolina Arruda Guedes, Carolline G. D’ assunção, Kamilla A. Dutra, José Vargas de Oliveira, Valéria Wanderley-Teixeira, Franklin M. Cunha, Álvaro Aguiar Coelho Teixeira, Douglas Rafael e Silva Barbosa
Publikováno v:
Chemico-Biological Interactions. 263:74-80
Spodoptera frugiperda is a major pest in several crops due to its polyphagous habit. Studies on the use of essential oils for pest control have been increasing over the years, presenting itself as a promising alternative with less environmental impac
Autor:
Vilmar C. Banderó-Filho, Erick V. S. Motta, Juliana de Carvalho da Costa, Jairo Kenupp Bastos, Astrid Sasse, Helen Sheridan, Marivane Lemos
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Nine new methylated galloylquinic acids were isolated from an aqueous fraction of Copaifera langsdorffii (Fabaceae-Caesalpinioideae) leaf hydroalcoholic extract (3-8, 11, 12, and 14), along with three known methylated galloylquinic acids (1, 2, and 1
Autor:
Jeferson S. Santos, Thaise Boeing, Sérgio Faloni de Andrade, Ricardo L.C. Albuquerque-Júnior, Luisa Mota da Silva, Ana Roseli S. Ribeiro, José Diego do Nascimento Valença, Sara M. Thomazzi
Publikováno v:
Chemico-Biological Interactions. 260:33-41
Many flavonoids have been shown to present good results for the treatment of gastric ulcers. Baicalein, a bioactive flavonoid derived from the Scutellaria baicalensis Georgi root, possesses several biological effects, such as anti-inflammatory and an
Autor:
Aidong Wen, Zhifu Yang, Jingwen Wang, Chao Zhao, Hai-Feng Tang, Ruili Li, Weiwei Li, Yi Ding, Meiyou Liu, Minna Yao, Yanhua Wang, Wei Zhang
Publikováno v:
Chemico-Biological Interactions. 331:109246
Colorectal cancer (CRC) represents one of the commonest malignancies around the world. PP9, a natural steroidal saponin, was firstly isolated from the rhizomes of Paris polyphylla var. latifolia. However, the therapeutic effects of PP9 on CRC and the