Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kun Lu"'
Autor:
Yun-Chung Hsiao, Richard S. Matulewicz, Scott E. Sherman, Ilona Jaspers, Michael L. Weitzman, Terry Gordon, Chih-Wei Liu, Yifei Yang, Kun Lu, Marc A. Bjurlin
Publikováno v:
Chemical Research in Toxicology. 36:630-642
Publikováno v:
Chemical research in toxicology. 35(1)
Cancer remains the second most frequent cause of death in human populations worldwide, which has been reflected in the emphasis placed on management of risk from environmental chemicals considered to be potential human carcinogens. The formation of D
Publikováno v:
Chem Res Toxicol
The human intestine is host to a vast microbial community: the gut microbiome (GM). The GM has been considered as a key modulator of human health in the past decade. In particular, several studies have supported that altered GM is associated with can
Publikováno v:
Chemical research in toxicology. 34(3)
Formation of DNA adducts is a key event during carcinogenesis. DNA adducts, if not repaired properly, can lead to mutations and cancer. DNA adducts have been frequently used as biomarkers to evaluate chemical exposure. Vinyl acetate monomer (VAM) is
Publikováno v:
Chemical Research in Toxicology; 1/17/2022, Vol. 35 Issue 1, p7-29, 23p
Publikováno v:
Chemical research in toxicology. 32(6)
Chronic arsenic exposure from drinking water is a global public health issue, which is associated with numerous human diseases and influences millions of people worldwide. The effects of arsenic exposure to the metabolic networks remain elusive. Here
Publikováno v:
Chemical research in toxicology. 32(1)
The gut microbiome is highly involved in numerous aspects of host physiology, from energy harvest to stress response, and can confer many benefits to the host. The gut microbiome development could be affected by genetic and environmental factors, inc
Autor:
Jiapeng Leng, Kun Lu, James A. Swenberg, Hadley J. Hartwell, Liang Chi, Xu Tian, Chih-Wei Liu
Publikováno v:
Chemical research in toxicology. 31(5)
Genomic instability caused by DNA-protein cross-link (DPCs)-induced DNA damage is implicated in disease pathogenesis, aging, and cancer development. The covalent linkages between DNA and protein are induced by chemical reactions catalyzed by the endo
Publikováno v:
Chemical research in toxicology. 30(12)
As the primary active substance in tobacco, nicotine affects the activity of the central nervous system, and its effects are sex-dependent. There are complex interactions between the gut and brain, and the gut microbiome can influence neuronal activi
Publikováno v:
Chemical Research in Toxicology. 29:949-951
The gut microbiome is deeply involved in numerous aspects of human health; however, it can be readily perturbed by environmental toxicants, such as arsenic. Meanwhile, the interaction among host, gut microbiome, and xenobiotics is a very complex dyna