Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jae J. Song"'
Publikováno v:
Cellular Signalling. 25:1288-1300
Curcumin as an anticancer agent was investigated in regards to its ability to regulate the switching of cancer cells from survival to necrotic cell death. At higher concentrations, curcumin induced ROS production leading to JNK and p38 phosphorylatio
Autor:
Bo K. Sun, Jae J. Song, Jina Kim, Hyo R. Yoon, Joo Hang Kim, So Y. Kim, Dongxu Kang, Sujin Kang
Publikováno v:
Cellular Signalling. 24:1444-1452
The combination of curcumin and TRAIL and their role in enhancing apoptotic cell death has been reported by many studies. However, the exact molecular mechanism of apoptosis mediated by curcumin and tumor necrosis factor-related apoptosis-inducing li
Autor:
Marco A. Alcala, Yong Tae Kwon, Miroslaw J. Szczepanski, Joo Hang Kim, So Young Kim, Jee Young An, David L. Bartlett, Yong J. Lee, Jae J. Song
Publikováno v:
Cellular Signalling. 22:553-563
We previously reported two modes of development of acquired TRAIL resistance: early phase and late phase [1]. In these studies, we observed that greater Akt activity and the expression of Bcl-xL were related mainly to the late phase of acquired TRAIL
Autor:
Jae J. Song, Yong J. Lee
Publikováno v:
Cellular Signalling. 20:892-906
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been shown to induce apoptosis through caspase activation in a number of cancer cell lines while displaying minimal or no toxicity on normal cells, suggesting that this protein may h
Publikováno v:
Cellular signalling. 27(6)
We previously showed that an increase of cellular Bcl-xL mediates acquired resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and knockdown of Bcl-xL expression greatly sensitized TRAIL-induced cytotoxicity. Here, we show t
Autor:
Hye Jin Choi, Suyeon Je, So Young Kim, Dongxu Kang, Jae J. Song, Yong sic Hwang, Zhezhu Han, Joo Hang Kim, Sujin Kang
Publikováno v:
Cellular signalling. 27(4)
Gemcitabine has been used most commonly as an anticancer drug to treat advanced pancreatic cancer patients. However, intrinsic or acquired resistance of pancreatic cancer to gemcitabine was also developed, which leads to very low five-year survival r
Publikováno v:
Cellular signalling. 25(1)
Previously, we showed that mitogen-activated protein kinase/extracellular signal-related kinase 4 (MEKK4) is responsible for p38 activation and that its activation during tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) treatment also
Autor:
Jae J. Song, Yong J. Lee
Publikováno v:
Cellular signalling. 19(3)
Exposure of mammalian cells to ultraviolet (UV) light or glucose deprivation activates c-Jun NH 2 -terminal protein kinase (JNK). However, the exact mechanism by which UV induces JNK activation is not yet understood completely. Previously, we have ob
Autor:
Bo K. Sun, Hyo R. Yoon, Joo Hang Kim, Jae J. Song, Jina Kim, Sujin Kang, Dongxu Kang, So Y. Kim
Publikováno v:
Cellular Signalling. 24:2407