Zobrazeno 1 - 10
of 42
pro vyhledávání: ''
Autor:
Wen-xing Qin, Han Wu, Ming-Da Wang, Hao Xing, Tian Yang, Juyuan Bu, Chao Li, Yifeng Liao, Lei Liang, Jun Han, Jin Zhang, Zhen-Li Li, Han Zhang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 6, Pp 2829-2842 (2018)
Background/Aims: Cullin 4A (CUL4A) is vital in cell survival, development, growth and cell cycle, it plays an important role in chaperone-mediated ubiquitination and interacts with TP53 in carcinogenesis. However, the clinicopathologic significance o
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 6, Pp 2429-2440 (2018)
Background/Aims: The chondroitin sulfate proteoglycan serglycin (SRGN), a hematopoietic cell granule proteoglycan, has been implicated in promoting tumor metastasis; however, the underlying mechanisms remain to be elucidated. The present study aimed
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 6, Pp 2517-2527 (2018)
Background/Aims: The purpose of our experiments was to investigate the targeting relationship of linc00515, miR-140-5p and ATG14 and to explore the roles of linc00515, miR-140-5p and ATG14 in autophagy and chemoresistance of melphalan-resistant multi
Autor:
Chen Wu, Xiaodong Li, Qi Zhou, Dachuan Zhang, Changping Wu, Xiao Zheng, Jingting Jiang, Bin Xu, Danxia Zhu, Wenwei Hu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 6, Pp 2493-2502 (2018)
Background/Aims: IL-1β is an important mediator of “inflammation-cancer" transformation through IL-1β/NF-κB/COX-2/HIF-1α signaling pathway, whereas certain portion of patients with lung adenocarcinoma (LUAD) still suffer from rapid tumor progre
Autor:
Jun Qin, Shao-Lan Qin, Yong Zhou, Yi-Er Qiu, Jian-Jun Chen, Ming Zhong, Yang Luo, Ran Cui, Min-Hao Yu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 4, Pp 1693-1703 (2018)
Background/Aims: ADAMTSs (A disintegrin and metalloprotease domains with thrombospondins motifs) are a family of extracellular proteases that have been related to both oncogenic and tumor-suppressive functions. The aim of the present study was to inv
Autor:
Sun Weiyan, Chen Jianbo, Lu Yefen, Jian-Jun Chen, Yi-An Xiang, Xue-Li Cai, Xiu-Mei Liu, Zheng-Zheng Li, Jing Lv, Wei-Jing Chen
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 5, Pp 1975-1985 (2018)
Background/Aims: Long noncoding RNAs (lncRNAs) have recently emerged as novel and potentially promising therapeutic targets in various cancers. However, the expression pattern and biological function of lncRNAs in glioma remain largely elusive. In th
Autor:
Yufu Tang, Wenping Zhou, Shu-Qun Cheng, Ruoyu Wang, Na Qiao, Zhongyi Sun, Shenhui Lin, Yibing Zhang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 3, Pp 1097-1107 (2018)
Background/Aims: 14-3-3ζ is involved in the regulation of PI3K/Akt pathway which is closely associated with carcinogenesis. However, the clinical significance of combined detection of 14-3-3ζ and p-Akt in hepatocellular carcinoma (HCC) remains uncl
Autor:
Yun Zuo, Qin Jiang, Xiaojing Shi, Cong Cao, Yu Song, Chen Ni, Zhi-Peng Chen, Yan Lv, Shao-Kai Wang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 3, Pp 1219-1229 (2018)
Background/Aims: Lymphocyte antigen 6 complex, locus E (LY6E) is a member of the lymphostromal cell membrane Ly6 superfamily protein. The present study investigated the clinical significance and potential biological function of LY6E in gastric cancer
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 2, Pp 991-1000 (2018)
Background/Aims: To investigate the role of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) in the clinical prognosis and cell biology of renal cell carcinoma (RCC). Methods: A total of 137 RCC tissues were evaluated by immunohistochemistry. The r
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 1, Pp 237-249 (2018)
Background/Aims: It is well established that many non-trophoblastic tumors secrete HCG (human chorionic gonadotropin) and that such secretion is correlated with the poor prognosis of tumor patients. This study aims to analyze the correlation between