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Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 6, Pp 2277-2292 (2018)
Background/Aims: In this study, we aimed to investigate the effects of genistein on the focal adhesion signaling pathway through its regulation of FAK . Genistein ultimately restored and alleviated estradiol-induced vascular endothelial injury. Metho
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 5, Pp 2071-2085 (2018)
Background/Aims: The cytokine interleukin-11 (IL-11) has important pro- and anti-inflammatory functions. It activates its target cells through binding to the IL-11 receptor (IL-11R), and the IL-11/IL-11R complex recruits a homodimer of glycoprotein 1
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 1, Pp 160-171 (2018)
Background/Aims: Lymphangiogenesis plays an important role in the pathogenesis of inflammatory bowel diseases (IBD), and vascular endothelial growth factor-C (VEGF-C) is a powerful lymphangiogenic factor. Adipose-derived stem cells (ADSCs) are a prom
Autor:
Seo Yihl Kim, Chang Woo Chae, Hyun Jik Lee, So Hee Ko, Jae Ryong Lim, Ho Jae Han, Jun Sung Kim, Young Hyun Jung, Chang-Kyu Lee, Gee Euhn Choi, Ji Young Oh
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 5, Pp 1749-1767 (2018)
Background/Aims: Glucose plays an important role in stem cell fate determination and behaviors. However, it is still not known how glucose contributes to the precise molecular mechanisms responsible for stem cell migration. Thus, we investigate the e
Autor:
Hongjie You, Limin Wang, Tiantian Liu, Jingyi Xue, Zheng Fan, Yuanyuan Zheng, Dali Luo, Shu Li, Lane Zhang, Zhipeng Sun
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 3, Pp 1042-1054 (2018)
Background/Aims: Upon Ca2+ store depletion, stromal interaction molecule 1 (STIM1) oligomerizes, redistributes near plasmalemma to interact with Ca2+ selective channel-forming subunit (Orai1) and initiates store-operated Ca2+ entry (SOCE). Ca2+/calmo
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 3, Pp 1207-1220 (2018)
Background/Aims: This study aims to predict the pro-angiogenic functions of monocytic-type myeloid-derived suppressor cells (M-MDSCs) derived from mice infected with Echinococcus granulosus. Methods: M-MDSCs were collected from Balb/c mice infected w
Autor:
Fang-Fang Chen, Lu Han, Lei Zhang, Di Wang, Ming Song, Zhi-Hao Wang, Meng-xiong Tang, Ming Zhong, Wei Zhang, Feng Wang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 4, Pp 1416-1432 (2018)
Background/Aims: Adipocyte-derived exosomes (ADEs) stimulate the activation of macrophages and contribute to the development of insulin resistance. Sonic Hedgehog (Shh) is an exosome-carrying protein and stimulates macrophages to secrete inflammatory
Publikováno v:
Cellular Physiology and Biochemistry, Vol 50, Iss 3, Pp 963-972 (2018)
Background/Aims: Preventing undesirable endothelial-mesenchymal transformation (EnMT) with repetitious in vitro expansion of human corneal endothelial cells (CECs) is a pivotal issue in cornea regeneration. Previous studies have shown that inhibition
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 3, Pp 932-946 (2018)
Background/Aims: Butein (2’,3,4,4’-Tetrahydroxychalcone), a polyphenol produced by several plants including Butea monoserpma, has been reported to exert potent anti-inflammatory activity but the mechanism remains unknown. In the present work we i
Autor:
Dwipanjan Sanyal, Sourav Chowdhury, Suparna Sarkar-Banerjee, Sib Sankar Roy, Tulika Mitra, Krishnananda Chattopadhyay
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 4, Pp 1658-1678 (2018)
Background/Aims: The conformation, folding and lipid binding properties of the intestinal fatty acid binding proteins (IFABP) have been extensively investigated. In contrast, the functional aspects of these proteins are not understood and matter of d