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Publikováno v:
Cellular immunology, 199(2), 89-96. ACADEMIC PRESS INC ELSEVIER SCIENCE
Previous studies involving the function and development of peripheral T cells have proposed that, in the rat, CD4(+)CD45RC(+)RT6(-) and CD4(+)CD45RC(-)RT6(+) T-cell subsets may represent Th1 and Th2 cells, respectively. Here we tested this hypothesis
Autor:
Jaap Kampinga, Herman Groen, Flip A. Klatter, Paul Nieuwenhuis, Auk S. Wubbena, Nicolaas H.C. Brons
Publikováno v:
Cellular Immunology. 163:113-119
In rats, RT6 and CD45RC are expressed by mature peripheral T cells. The underrepresentation of T cells expressing these markers in the T lymphocytopenic BB rat might therefore be a reflection of a relatively immature T cell population. With the use o