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Publikováno v:
Cells; Volume 11; Issue 20; Pages: 3219
Pannexin1 (Panx1) is expressed in both neurons and glia where it forms ATP-permeable channels that are activated under pathological conditions such as epilepsy, migraine, inflammation, and ischemia. Membrane lipid composition affects proper distribut
Publikováno v:
Cells; Volume 11; Issue 9; Pages: 1478
Bitter taste receptors (T2Rs) are G protein-coupled receptors (GPCRs) expressed in various cell types including ciliated airway epithelial cells and macrophages. T2Rs in these two airway innate immune cell types are activated by bitter products, incl
Autor:
Isaure Vanmeerbeek, Jannes Govaerts, Raquel S. Laureano, Jenny Sprooten, Stefan Naulaerts, Daniel M. Borras, Damya Laoui, Massimiliano Mazzone, Jo A. Van Ginderachter, Abhishek D. Garg
Publikováno v:
Cells. 11:3890
Tumour-associated macrophages (TAMs) are essential players in the tumour microenvironment (TME) and modulate various pro-tumorigenic functions such as immunosuppression, angiogenesis, cancer cell proliferation, invasion and metastasis, along with res
Autor:
Andrey Bogorodskiy, Ivan Okhrimenko, Dmitrii Burkatovskii, Philipp Jakobs, Ivan Maslov, Valentin Gordeliy, Norbert A. Dencher, Thomas Gensch, Wolfgang Voos, Joachim Altschmied, Judith Haendeler, Valentin Borshchevskiy
Publikováno v:
Cells
Cells 10(12), 3528-(2021). doi:10.3390/cells10123528
Cells, Vol 10, Iss 3528, p 3528 (2021)
Cells 10(12), 3528-(2021). doi:10.3390/cells10123528
Cells, Vol 10, Iss 3528, p 3528 (2021)
Mitochondria play a critical role in providing energy, maintaining cellular metabolism, and regulating cell survival and death. To carry out these crucial functions, mitochondria employ more than 1500 proteins, distributed between two membranes and t
Autor:
Jacob G. Kurdys, Edwin J. Vazquez, Mariana G. Rosca, Carmen Avramut, Alexis Paige Vicenzi, Leana Rose Weiler, Naveen Kumar Mekala, Neli Ragina
Publikováno v:
Cells
Volume 10
Issue 11
Cells, Vol 10, Iss 3152, p 3152 (2021)
Volume 10
Issue 11
Cells, Vol 10, Iss 3152, p 3152 (2021)
Metabolic syndrome increases the risk for cardiovascular disease including metabolic cardiomyopathy that may progress to heart failure. The decline in mitochondrial metabolism is considered a critical pathogenic mechanism that drives this progression
Autor:
Ana Rita Ribeiro, Catarina Barros, Fábio M. F. Santos, Maria Vaz Pinto, Pedro M. P. Gois, Adelaide Fernandes, Uwe Pischel
Publikováno v:
Cells
Volume 10
Issue 11
Cells, Vol 10, Iss 3163, p 3163 (2021)
Volume 10
Issue 11
Cells, Vol 10, Iss 3163, p 3163 (2021)
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that is characterized by the presence of demyelinated regions with accumulated myelin lipid debris. Importantly, to allow effective remyelination, such debris must be cl
Autor:
Audrey M Sénécal, Antoine Y Bouchard, Laurent Cappadocia, Kim Ghilarducci, Valérie C. Cabana, Marc P. Lussier, Saïd Kourrich
Publikováno v:
Cells
Volume 10
Issue 11
Cells, Vol 10, Iss 3063, p 3063 (2021)
Volume 10
Issue 11
Cells, Vol 10, Iss 3063, p 3063 (2021)
Developmental and epileptic encephalopathies (DEE) are rare and serious neurological disorders characterized by severe epilepsy with refractory seizures and a significant developmental delay. Recently, DEE73 was linked to genetic alterations of the R
Publikováno v:
Cells
Volume 10
Issue 11
Cells, Vol 10, Iss 3038, p 3038 (2021)
Volume 10
Issue 11
Cells, Vol 10, Iss 3038, p 3038 (2021)
Cell lines are widely used as in vitro model systems and substitute for animal experiments. The frequently used Caco-2 cell line is considered to reflect characteristics of differentiated intestinal epithelium. However, the need to culture the cells
Autor:
Vincenzo De Leo, Sofia Passaponti, Laura Governini, Francesca Paola Luongo, Alice Luddi, Giuseppe Morgante, Paola Piomboni, Claudia Landi, Bianca Semplici
Publikováno v:
Cells
Cells, Vol 10, Iss 3127, p 3127 (2021)
Volume 10
Issue 11
Cells, Vol 10, Iss 3127, p 3127 (2021)
Volume 10
Issue 11
Bitter taste receptors (TAS2RS) expression is not restricted to the oral cavity and the presence of these receptors in the male reproductive system and sperm provides insights into their possible role in human reproduction. To elucidate the potential
Autor:
David M. van Reyk, Dikaia Xenaki, Patrick He, Brian G. Oliver, Sandra Rutting, Michael Papanicolaou, Alaina J. Ammit
Publikováno v:
Cells
Cells; Volume 10; Issue 12; Pages: 3351
Cells, Vol 10, Iss 3351, p 3351 (2021)
Cells; Volume 10; Issue 12; Pages: 3351
Cells, Vol 10, Iss 3351, p 3351 (2021)
Chronic airway inflammation and oxidative stress play crucial roles in the pathogenesis of chronic inflammatory lung diseases, with airway inflammation being a key driving mechanism of oxidative stress in the lungs. Inflammatory responses in the lung