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Autor:
Francesco Costanzo, Stefania Scalise, Elvira Immacolata Parrotta, Luana Scaramuzzino, Clara Zannino, Valeria Lucchino, Michela Lo Conte, Flavia Biamonte, Alessandro Sacco, Giovanni Cuda
Publikováno v:
Cells
Volume 10
Issue 9
Cells, Vol 10, Iss 2431, p 2431 (2021)
Volume 10
Issue 9
Cells, Vol 10, Iss 2431, p 2431 (2021)
Embryonic stem cells (ESCs) are pluripotent cells with indefinite self-renewal ability and differentiation properties. To function properly and maintain genomic stability, ESCs need to be endowed with an efficient repair system as well as effective r
Autor:
Rui Fu, Amber Baldwin, Elisabeth Murphy, Kimberly Wellman, William E. Rainey, Neelanjan Mukherjee, Juilee Rege
Publikováno v:
Cells
Cells, Vol 10, Iss 2376, p 2376 (2021)
Volume 10
Issue 9
Cells, Vol 10, Iss 2376, p 2376 (2021)
Volume 10
Issue 9
Adrenal steroid hormone production is a dynamic process stimulated by adrenocorticotropic hormone (ACTH) and angiotensin II (AngII). These ligands initialize a rapid and robust gene expression response required for steroidogenesis. Here, we compare t
Publikováno v:
Cells
Volume 10
Issue 8
Cells, Vol 10, Iss 2089, p 2089 (2021)
Volume 10
Issue 8
Cells, Vol 10, Iss 2089, p 2089 (2021)
In Notch signaling, the Jagged1-Notch3 ligand-receptor pairing is implicated for regulating the phenotype maturity of vascular smooth muscle cells. However, less is known about the role of Jagged1 presentation strategy in this regulation. In this stu
Publikováno v:
Cells
Volume 10
Issue 6
Cells, Vol 10, Iss 1463, p 1463 (2021)
Volume 10
Issue 6
Cells, Vol 10, Iss 1463, p 1463 (2021)
This study aims to obtain sufficient corneal endothelial cells for regenerative application. We examined the combinatory effects of Rho-associated kinase (ROCK) inhibitor Y-27632 and mesenchymal stem cell-derived conditioned medium (MSC-CM) on the pr
Autor:
Barbara Choromańska, Marcin Moniuszko, Adrian Chabowski, Elżbieta Supruniuk, Piotr Myśliwiec, Bartłomiej Łukaszuk, Agnieszka Mikłosz, Kamil Grubczak
Publikováno v:
Cells
Volume 10
Issue 6
Cells, Vol 10, Iss 1515, p 1515 (2021)
Volume 10
Issue 6
Cells, Vol 10, Iss 1515, p 1515 (2021)
TBC1D4 (AS160) and TBC1D1 are Rab GTPase-activating proteins that play a key role in the regulation of glucose and possibly the transport of long chain fatty acids (LCFAs) into muscle and fat cells. Knockdown (KD) of TBC1D4 increased CD36/SR-B2 and F
Autor:
Shimeng Qiu, Mima Shinji, Tadahiro Hashita, Yaling Li, Tamihide Matsunaga, Takahiro Iwao, Yuki Imakura
Publikováno v:
Cells
Volume 10
Issue 4
Cells, Vol 10, Iss 812, p 812 (2021)
Volume 10
Issue 4
Cells, Vol 10, Iss 812, p 812 (2021)
The endoderm, differentiated from human induced pluripotent stem cells (iPSCs), can differentiate into the small intestine and liver, which are vital for drug absorption and metabolism. The development of human iPSC-derived enterocytes (HiEnts) and h
Autor:
Noriaki Nagai, Kazuyoshi Imaizumi, Eri Kubo, Ei-ichi Miyachi, Mahito Ohkuma, Masayuki Horiguchi, Noriko Hiramatsu, Natsuko Hatsusaka, Naoki Yamamoto, Masashi Kondo, Shun Takeda, Hiroshi Sasaki
Publikováno v:
Cells
Volume 10
Issue 4
Cells, Vol 10, Iss 743, p 743 (2021)
Volume 10
Issue 4
Cells, Vol 10, Iss 743, p 743 (2021)
Regenerative medicine in ophthalmology that uses induced pluripotent stem cells (iPS) cells has been described, but those studies used iPS cells derived from fibroblasts. Here, we generated iPS cells derived from iris cells that develop from the same
Autor:
Makoto Seki, Toshiaki Numajiri, Tsunao Kishida, Osam Mazda, Fiona Louis, Kenji Takahashi, Yoshihiro Sowa, Seiji Sawai
Publikováno v:
Cells
Volume 10
Issue 3
Cells, Vol 10, Iss 605, p 605 (2021)
Volume 10
Issue 3
Cells, Vol 10, Iss 605, p 605 (2021)
There is a need in plastic surgery to prepare autologous adipocytes that can be transplanted in patients to reconstruct soft tissue defects caused by tumor resection, including breast cancer, and by trauma and other diseases. Direct conversion of som
Publikováno v:
Cells
Volume 10
Issue 4
Cells, Vol 10, Iss 719, p 719 (2021)
Volume 10
Issue 4
Cells, Vol 10, Iss 719, p 719 (2021)
The aim of our work was to develop a protocol enabling a derivation of mesenchymal stem/stromal cell (MSC) subpopulation with increased expression of pluripotent and neural genes. For this purpose we used a 3D spheroid culture system optimal for neur
Autor:
Markus Mandl, Sonja A. Wagner, Saphira Baumgarten, Stefan Lechner, Florian M. Hatzmann, G. Jan Wiegers, Werner Zwerschke, Asim Ejaz, Camille Brucker, Monika Mattesich, Gerhard Pierer, Marit Zwierzina, Petra Waldegger, Tina Rauchenwald
Publikováno v:
Cells
Volume 10
Issue 2
Cells, Vol 10, Iss 214, p 214 (2021)
Volume 10
Issue 2
Cells, Vol 10, Iss 214, p 214 (2021)
We explore the status of quiescence, stemness and adipogenic differentiation capacity in adipose stem/progenitor cells (ASCs) ex vivo, immediately after isolation from human subcutaneous white adipose tissue, by sorting the stromal vascular fraction