Zobrazeno 1 - 10
of 23
pro vyhledávání: '"WEI LU"'
Autor:
Xiaoxue Jiang, Kan Liu, Haizhou Jiang, Hanrui Yin, En-duo Wang, Hong Cheng, Feixiang Yuan, Fei Xiao, Fenfen Wang, Wei Lu, Bo Peng, Yousheng Shu, Xiaoying Li, Shanghai Chen, Feifan Guo
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111984- (2023)
Summary: Lysosomal amino acid accumulation is implicated in several diseases, but its role in insulin resistance, the central mechanism to type 2 diabetes and many metabolic diseases, is unclear. In this study, we show the hepatic expression of lysos
Externí odkaz:
https://doaj.org/article/59ed0553eff74c9cbe99874180fda098
Publikováno v:
Cell Reports, Vol 34, Iss 12, Pp 108899- (2021)
Summary: Tonic inhibition mediated by extrasynaptic γ-aminobutyric acid type A receptors (GABAARs) critically regulates neuronal excitability and brain function. However, the mechanisms regulating tonic inhibition remain poorly understood. Here, we
Externí odkaz:
https://doaj.org/article/c5b6adef800d4908a6cd81682988fdb7
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 471-478 (2016)
In the mammalian brain, GABAergic synaptic transmission provides inhibitory balance to glutamatergic excitatory drive and controls neuronal output. The molecular mechanisms underlying the development of GABAergic synapses remain largely unclear. Here
Externí odkaz:
https://doaj.org/article/0083f2ffe05c4d8482a43faaa74c3ceb
Publikováno v:
Cell Reports, Vol 12, Iss 5, Pp 743-751 (2015)
Membrane trafficking and spinogenesis contribute significantly to changes in synaptic strength during development and in various paradigms of synaptic plasticity. GTPases of the dynamin family are key players regulating membrane trafficking. Here, we
Externí odkaz:
https://doaj.org/article/da6b07987af34f8cbb65c3dfda3e45e8
Publikováno v:
Cell Reports, Vol 2, Iss 6, Pp 1736-1746 (2012)
Efforts to develop a vaccine against HIV have so far met with limited success. Given that CD4+ T cell activation drives the initial burst of viral replication, we explored in macaques whether an oral vaccine comprised of Lactobacillus plantarum, a co
Externí odkaz:
https://doaj.org/article/e048dfa17c1d418f826da1d53be0e4a8
Autor:
Yunpeng Dai, Binbin Wang, Jiaxin Wang, Xiaocui Wei, Xing Liu, Xu Che, Junxia Li, Wei Lun Ng, Lin-Fa Wang, Yang Li
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114581- (2024)
Summary: Bats harbor highly virulent viruses that can infect other mammals, including humans, posing questions about their immune tolerance mechanisms. Bat cells employ multiple strategies to limit virus replication and virus-induced immunopathology,
Externí odkaz:
https://doaj.org/article/e6665ca8c7884e1093e2741c60994d0d
Autor:
Rakhee Bajaj, B. Leticia Rodriguez, William K. Russell, Amanda N. Warner, Lixia Diao, Jing Wang, Maria G. Raso, Wei Lu, Khaja Khan, Luisa S. Solis, Harsh Batra, Ximing Tang, Jared F. Fradette, Samrat T. Kundu, Don L. Gibbons
Publikováno v:
Cell Reports. 40:111429
Lung cancer is a highly aggressive and metastatic disease responsible for approximately 25% of all cancer-related deaths in the United States. Using high-throughput in vitro and in vivo screens, we have previously established Impad1 as a driver of lu
Autor:
Dandan, Qian, Wei, Li, Jinwen, Xue, Yi, Wu, Ziling, Wang, Tao, Shi, Songting, Li, Jingxuan, Yang, Shi, Qiu, Shaoli, Wang, Yousheng, Shu, Liang, Chen, Qiao, Wang, Ti-Fei, Yuan, Douglas, Zhou, Wei, Lu
Publikováno v:
Cell Reports. 40:111111
Enhanced beta oscillations within the cortico-basal ganglia-thalamic (CBT) network are correlated with motor deficits in Parkinson's disease (PD), whose generation has been associated recently with amplified network dynamics in the striatum. However,
Publikováno v:
Cell Reports, Vol 34, Iss 12, Pp 108899-(2021)
Cell reports
Cell reports
SUMMARY Tonic inhibition mediated by extrasynaptic γ-aminobutyric acid type A receptors (GABAARs) critically regulates neuronal excitability and brain function. However, the mechanisms regulating tonic inhibition remain poorly understood. Here, we r
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113665- (2024)
Summary: mRNA vaccines have proven to be pivotal in the fight against COVID-19. A recommended booster, given 3 to 4 weeks post the initial vaccination, can substantially amplify protective antibody levels. Here, we show that, compared to contralatera
Externí odkaz:
https://doaj.org/article/4fc508bc76fc45f1ba49b1496cbd2eaa