Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Michael Snyder"'
Autor:
Xin Wei, Ming-Shian Tsai, Liang Liang, Liuyiqi Jiang, Chia-Jui Hung, Laura Jelliffe-Pawlowski, Larry Rand, Michael Snyder, Chao Jiang
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114078- (2024)
Summary: The vaginal microbiome’s composition varies among ethnicities. However, the evolutionary landscape of the vaginal microbiome in the multi-ethnic context remains understudied. We perform a systematic evolutionary analysis of 351 vaginal mic
Externí odkaz:
https://doaj.org/article/50c8cc10d5de4f2abe9b7f931171f35d
Autor:
Andreea Manole, Thomas Wong, Amanda Rhee, Sammy Novak, Shao-Ming Chin, Katya Tsimring, Andres Paucar, April Williams, Traci Fang Newmeyer, Simon T. Schafer, Idan Rosh, Susmita Kaushik, Rene Hoffman, Songjie Chen, Guangwen Wang, Michael Snyder, Ana Maria Cuervo, Leo Andrade, Uri Manor, Kevin Lee, Jeffrey R. Jones, Shani Stern, Maria C. Marchetto, Fred H. Gage
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113466- (2023)
Summary: Biallelic mutations in the gene that encodes the enzyme N-glycanase 1 (NGLY1) cause a rare disease with multi-symptomatic features including developmental delay, intellectual disability, neuropathy, and seizures. NGLY1’s activity in human
Externí odkaz:
https://doaj.org/article/e02b3ae04a344993bec4fbd3628df05f
Autor:
Yingwei Hu, Jianbo Pan, Punit Shah, Minghui Ao, Stefani N. Thomas, Yang Liu, Lijun Chen, Michael Schnaubelt, David J. Clark, Henry Rodriguez, Emily S. Boja, Tara Hiltke, Christopher R. Kinsinger, Karin D. Rodland, Qing Kay Li, Jiang Qian, Zhen Zhang, Daniel W. Chan, Hui Zhang, Akhilesh Pandey, Amanda Paulovich, Andrew Hoofnagle, Bing Zhang, D.R. Mani, Daniel C. Liebler, David F. Ransohoff, David Fenyo, David L. Tabb, Douglas A. Levine, Eric Kuhn, Forest M. White, Gordon A. Whiteley, Heng Zhu, Ie-Ming Shih, Jasmin Bavarva, Jason E. McDermott, Jeffrey Whiteaker, Karen A. Ketchum, Karl R. Clauser, Kelly Ruggles, Kimberly Elburn, Li Ding, Linda Hannick, Lisa J. Zimmerman, Mark Watson, Mathangi Thiagarajan, Matthew J.C. Ellis, Mauricio Oberti, Mehdi Mesri, Melinda E. Sanders, Melissa Borucki, Michael A. Gillette, Michael Snyder, Nathan J. Edwards, Negin Vatanian, Paul A. Rudnick, Peter B. McGarvey, Philip Mertins, R. Reid Townsend, Ratna R. Thangudu, Richard D. Smith, Robert C. Rivers, Robert J.C. Slebos, Samuel H. Payne, Sherri R. Davies, Shuang Cai, Stephen E. Stein, Steven A. Carr, Steven J. Skates, Subha Madhavan, Tao Liu, Xian Chen, Yingming Zhao, Yue Wang, Zhiao Shi
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108276- (2020)
Summary: Many gene products exhibit great structural heterogeneity because of an array of modifications. These modifications are not directly encoded in the genomic template but often affect the functionality of proteins. Protein glycosylation plays
Externí odkaz:
https://doaj.org/article/687878b78b8f4a70bfe6276db55dbef8
Autor:
Indumathi Chennamsetty, Michael Coronado, Kévin Contrepois, Mark P. Keller, Ivan Carcamo-Orive, John Sandin, Giovanni Fajardo, Andrew J. Whittle, Mohsen Fathzadeh, Michael Snyder, Gerald Reaven, Alan D. Attie, Daniel Bernstein, Thomas Quertermous, Joshua W. Knowles
Publikováno v:
Cell Reports, Vol 17, Iss 2, Pp 527-540 (2016)
We recently identified human N-acetyltransferase 2 (NAT2) as an insulin resistance (IR) gene. Here, we examine the cellular mechanism linking NAT2 to IR and find that Nat1 (mouse ortholog of NAT2) is co-regulated with key mitochondrial genes. RNAi-me
Externí odkaz:
https://doaj.org/article/3b9b9363e5c4430f9d5342df98dc00e0
Autor:
Gavin M. Traber, Brittany Lee-McMullen, Michael Snyder, Masanori Honsho, Ria S. Sood, Kévin Contrepois, Yukio Fujiki, Scott J. Dixon, Michael C. Bassik, Michael M. Dubreuil, Kanji Okumoto, David W. Morgens
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1417-1433.e7 (2020)
Cell reports, vol 30, iss 5
Cell reports, vol 30, iss 5
Summary: Reactive oxygen species (ROS) play critical roles in metabolism and disease, yet a comprehensive analysis of the cellular response to oxidative stress is lacking. To systematically identify regulators of oxidative stress, we conducted genome
Autor:
Yang Liu, Mauricio Oberti, Samuel H. Payne, Zhiao Shi, Minghui Ao, Mathangi Thiagarajan, D. R. Mani, Karen A. Ketchum, Jeffrey R. Whiteaker, Henry Rodriguez, Peter B. McGarvey, Xian Chen, Karl R. Clauser, Nathan Edwards, Amanda G. Paulovich, Shuang Cai, David L. Tabb, Heng Zhu, David F. Ransohoff, Mark A. Watson, Andrew N. Hoofnagle, Kelly V. Ruggles, Jiang Qian, Karin D. Rodland, Qing Kay Li, Daniel C. Liebler, Yingwei Hu, Hui Zhang, Christopher R. Kinsinger, Akhilesh Pandey, Tara Hiltke, Stephen E. Stein, Lijun Chen, Eric Kuhn, Richard D. Smith, Matthew J. Ellis, Subha Madhavan, Linda Hannick, Punit Shah, Kimberly Elburn, Yingming Zhao, Bing Zhang, Robert J.C. Slebos, Daniel W. Chan, Zhen Zhang, Jasmin H. Bavarva, Sherri R. Davies, David J. Clark, Li Ding, Mehdi Mesri, Jianbo Pan, Melinda E. Sanders, Douglas A. Levine, Forest M. White, Lisa J. Zimmerman, Steven A. Carr, Michael A. Gillette, Tao Liu, Yue Wang, Robert Rivers, Melissa Borucki, David Fenyö, Steven J. Skates, Ie Ming Shih, Gordon Whiteley, Michael Snyder, Raymond R. Townsend, Philip Mertins, Ratna R. Thangudu, Paul A. Rudnick, Michael Schnaubelt, Negin Vatanian, Jason E. McDermott, Stefani N. Thomas, Emily S. Boja
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108276-(2020)
Cell Rep
Cell Rep
SUMMARY: Many gene products exhibit great structural heterogeneity because of an array of modifications. These modifications are not directly encoded in the genomic template but often affect the functionality of proteins. Protein glycosylation plays
Autor:
Daniel Bernstein, Joshua W. Knowles, Gerald M. Reaven, Giovanni Fajardo, Michael Coronado, Indumathi Chennamsetty, Thomas Quertermous, Michael Snyder, Andrew J. Whittle, Mark P. Keller, John Sandin, Kévin Contrepois, Ivan Carcamo-Orive, Alan D. Attie, Mohsen Fathzadeh
Publikováno v:
Cell Reports, Vol 17, Iss 2, Pp 527-540 (2016)
We recently identified human N-acetyltransferase 2 (NAT2) as an insulin resistance (IR) gene. Here we examine the cellular mechanism linking NAT2 to IR and find that Nat1 (mouse ortholog of NAT2) is co-regulated with key regulators of mitochondria. R
Autor:
Benjamin Meder, Wu Wei, Shannon Rego, Michael Gotthardt, Michael Snyder, Chenchen Zhu, Andrea Cipriano, Ioannis Karakikes, Gilles Millat, Lars M. Steinmetz, Jingyan Wu, Zhenyu Xu, Martin Liss, Mark Mercola, Francesca Briganti, Han Sun
Publikováno v:
Cell reports
SUMMARY Recent advances in induced pluripotent stem cell (iPSC) technology and directed differentiation of iPSCs into cardiomyocytes (iPSC-CMs) make it possible to model genetic heart disease in vitro. We apply CRISPR/Cas9 genome editing technology t
Autor:
Michael Snyder, Andrew M. Lipchik, James M. Ford, Benjamin Geller, Allison W. Kurian, Guangwen Wang, Joshua J. Gruber, Natalie Jäger, Justin Chen
Publikováno v:
Cell Reports, Vol 28, Iss 8, Pp 2182-2193.e6 (2019)
Summary: Individuals with a single functional copy of the BRCA2 tumor suppressor have elevated risks for breast, ovarian, and other solid tumor malignancies. The exact mechanisms of carcinogenesis due to BRCA2 haploinsufficiency remain unclear, but o