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Autor:
Masako Fujiyama, James L. Carmalt, Brendan G. Murray, Tanya Duke, Santosh Jagadeeshan, Xiaojie Luan, Julian S. Tam, Monique Burmester, Yen Le, Kurtis J. Swekla, Terry E. Machen, Verónica A. Campanucci, Juan P. Ianowski, Bridget Gray, Shannon G. Beazley, Alan M Shipley
Publikováno v:
Cell Reports, Vol 37, Iss 1, Pp 109795-(2021)
Summary: A controversial hypothesis pertaining to cystic fibrosis (CF) lung disease is that the CF transmembrane conductance regulator (CFTR) channel fails to inhibit the epithelial Na+ channel (ENaC), yielding increased Na+ reabsorption and airway d
Autor:
Peter Tontonoz, Thomas Q. de Aguiar Vallim, Paolo Parini, Stephanie M. Marshall, Rosanne M. Crooke, H. Alex Brown, Aldon J. Lusis, Daniel Ferguson, Amy C. Burrows, Mark J. Graham, J. Mark Brown, Manya Warrier, Stanley L. Hazen, Xiuli Liu, Rebecca C. Schugar, Ryan E. Temel, Jeff W. Chou, Jessica Sacks, David S. Myers, Allison L. McDaniel, Richard G. Lee, Amanda L. Brown, Diana M. Shih, Zeneng Wang, Xin Rong, Anthony D. Gromovsky, Pavlina T. Ivanova
Publikováno v:
Cell Reports, Vol 10, Iss 3, Pp 326-338 (2015)
Cell reports, vol 10, iss 3
Cell reports, vol 10, iss 3
SummaryCirculating levels of the gut microbe-derived metabolite trimethylamine-N-oxide (TMAO) have recently been linked to cardiovascular disease (CVD) risk. Here, we performed transcriptional profiling in mouse models of altered reverse cholesterol