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Publikováno v:
Cell Proliferation. 55
Nucleotide oligomerization domain receptor 1 (NOD1) mediates host recognition of pathogenic bacteria in periodontium. However, the specific role of NOD1 in regulating osteogenesis is unclear. Therefore, this study focused on the activation status of
Autor:
Min Chen, Xia Wang, Chuan Li, Ting Lan, Yuhui Wei, Chengcheng Tang, Xiaoqing Zhou, Renping Zhou, Alessandro Rosa, Xi Zheng, Song Ang, Kun Zhang, Qingjian Zou, Liangxue Lai
Publikováno v:
Cell Proliferation. 55
Transplantation of neural progenitor cells (NPCs) derived from human-induced pluripotent stem cells (hiPSCs) is one of the promising treatment strategies for motor neuron diseases (MNDs). However, the inefficiency in committed differentiation of NPCs
Publikováno v:
Cell Proliferation. 55
Human pluripotent stem cells (hPSC) have the capability to deliver novel cell-based medicines that could transform medical treatments for a wide range of diseases including age-related degenerative disorders and traumatic injury. In spite of signific
Autor:
Jia Guo, Feng Zhou, Zhi Liu, Yuan Cao, Wanming Zhao, Zheru Zhang, Qiming Zhai, Yan Jin, Bei Li, Fang Jin
Publikováno v:
Cell proliferation. 55(12)
The treatment of bone defects by stem cells (MSCs) has achieved limited success over the recent few decades. The emergence of exosomes provides a new strategy for bone regeneration. Here, we aimed to investigate the effect and mechanisms of exosomes
Publikováno v:
Cell Proliferation. 55
As a result of the current limitation of therapeutic strategies, the repair and regeneration of oviduct injuries required an alternative treatment. We present a novel approach to treat oviduct injuries through a dental pulp stem cells (DPSCs)-based t
Autor:
Yeonmi Lee, Minchul Kim, Miju Lee, Seongjun So, Soon‐Suk Kang, Jiwan Choi, Deokhoon Kim, Hyohoon Heo, Sung Soo Lee, Hee Ra Park, Jung Jae Ko, Jihwan Song, Eunju Kang
Publikováno v:
Cell Proliferation. 55
Patient-derived induced pluripotent stem cells (iPSCs) are materials that can be used for autologous stem cell therapy. We screened mtDNA mutations in iPSCs and iPSC-derived neuronal cells from patients with Alzheimer's disease (AD). Also, we investi
Publikováno v:
Cell Proliferation. 55
For use in regenerative medicine, large-scale manufacturing of human pluripotent stem cells (hPSCs) under current good manufacturing practice (cGMPs) is required. Much progress has been made since culturing under static two-dimensional (2D) condition
Autor:
Mingkang Chen, Xiying Mao, Darui Huang, Jiaona Jing, Wenjun Zou, Peiyao Mao, Mengting Xue, Wenjie Yin, Ruiwen Cheng, Yan Gao, Youjin Hu, Songtao Yuan, Qinghuai Liu
Publikováno v:
Cell Proliferation. 55
Stem cell-derived photoreceptor replacement therapy is a promising strategy for the treatment of retinal degenerative disease. The development of 3D retinal organoids has permitted the production of photoreceptors. However, there is no strategy to en
Publikováno v:
Cell proliferation. 55(9)
The skin exhibits tremendous regenerative potential, as different types of progenitor and stem cells regulate skin homeostasis and damage. However, in vitro primary keratinocytes present with several drawbacks, such as high donor variability, short l
Publikováno v:
Cell Proliferation. 55
Basic research on human pluripotent stem cell (hPSC)-derived cardiomyocytes (CMs) for cardiac regenerative therapy is one of the most active and complex fields to achieve this alternative to heart transplantation and requires the integration of medic